Inhaltsverzeichnis
Geneviève Almouzni
Nuclear Dynamics – Institut Curie/CNRS UMR 3664, Paris, France
Organisation of Heterochromatin Domains
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The Almouzni lab’s major scientific objective will be to gain data enabling researchers to model nucleosome assembly with distinct variants and organisation of heterochromatin domains, to assess their plasticity/stability throughout the cell cycle and when challenged under various perturbations. For this, the Almouzni lab will use biochemical and cellular assays involving protein complexes (such as recombinant histone chaperones, histone H3 variants, HP1, epitope tagged in vivo) to study the dynamics and modifications of histone H3 variants and heterochromatin proteins during the cell cycle.
| PhD students: | Post-docs: | |||
| Emmanuelle SZENKER Paolo BEUZER Kelly ROMEO Dan FILIPESCU Salomé ADAM |
FR IT FR RO FR |
Ekaterina BOYARCHUK Miguel CASANOVA Zachary GURARD-LEVIN Sebastian MÜLLER Rocio MONTES DE OCA Lisa PRENDERGAST Gaston SORIA Adam WOOLFE |
RU PT USA DE MX IE AR UK |
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Latest publications
Chromatin dynamics after DNA damage: The legacy of the access-repair-restore model.
26429064 – 2015-10-03
DNA Repair (Amst) 2015 Sep 15;
MCM2 binding to histones H3-H4 and ASF1 supports a tetramer-to-dimer model for histone inheritance at the replication fork.
26243657 – 2015-08-06
Nat Struct Mol Biol 2015 Aug 5;22(8):587-9
HJURP Involvement in De Novo CenH3(CENP-A) and CENP-C Recruitment.
25843710 – 2015-04-07
Cell Rep 2015 Apr 7;11(1):22-32
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