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Systems biology

Philipp A. Steffen, João P. Fonseca, Leonie Ringrose, published online at BioEssays: 22 AUG 2012
This review explores the application of quantitative and mathematical approaches to mechanisms of epigenetic regulation
onlinelibrary.wiley link

Supremely well-written story about how a small team of experimentalists and theoreticians collaborated to develop a theoretical model; why it is good for them to collaborate, and how these collaborations can be most productive.

by David G. Drubin and George Oster

link to abstract - link to pdf

GenoSpace has launched a cloud-based software-as-a-service (SaaS) computing platform. According to Quankenbush, GenoSpace CEO, the storage and SaaS platform provides access to a variety of genomic and phenotypic data.
MHT link

In thinking about complexity, it's frequently invoked that the whole is greater than the sum of its parts. This notion serves as one of the motivating principles of systems biology, which seeks to understand the emergent properties of complex biological systems. Among many biologists, systems biology is also synonymous with the use of particular approaches, including high-throughput techniques, large-scale integration of datasets, and computational modeling to probe system behaviors.
Cell link

News flash

Missing link in epigenetics could explain conundrum of disease inheritance

08-07-2016 - All News

The process by which a mother’s diet during pregnancy can permanently affect her offspring’s attributes, such as weight, could be strongly influenced by genetic variation in an unexpected part of...

Epigenetic switch for obesity

08-02-2016 - All News

Obesity can sometimes be shut down It is well known that a predisposition to adiposity lies in our genes. A new study by researchers at the Max Planck Institute of Immunobiology...