Philipp A. Steffen, João P. Fonseca, Leonie Ringrose, published online at BioEssays: 22 AUG 2012
This review explores the application of quantitative and mathematical approaches to mechanisms of epigenetic regulation
onlinelibrary.wiley link
Supremely well-written story about how a small team of experimentalists and theoreticians collaborated to develop a theoretical model; why it is good for them to collaborate, and how these collaborations can be most productive.
by David G. Drubin and George Oster
In thinking about complexity, it's frequently invoked that the whole is greater than the sum of its parts. This notion serves as one of the motivating principles of systems biology, which seeks to understand the emergent properties of complex biological systems. Among many biologists, systems biology is also synonymous with the use of particular approaches, including high-throughput techniques, large-scale integration of datasets, and computational modeling to probe system behaviors.
Cell link
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The process by which a mother’s diet during pregnancy can permanently affect her offspring’s attributes, such as weight, could be strongly influenced by genetic variation in an unexpected part of...
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