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Nicholas Luscombe

Cancer Research UK, London Research Institute

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Latest publications

Intra-Tumor Genetic Heterogeneity in Wilms Tumor: Clonal Evolution and Clinical Implications.

27333041 - 2016-06-23
EBioMedicine 2016 May 27;
Cresswell GD, Apps JR, Chagtai T, Mifsud B, Bentley CC, Maschietto M, Popov SD, Weeks ME, Olsen ØE, Sebire NJ, Pritchard-Jones K, Luscombe NM, Williams RD, Mifsud W

Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation.

27183194 - 2016-05-18
Nat Struct Mol Biol 2016 May 16;
Chlamydas S, Holz H, Samata M, Chelmicki T, Georgiev P, Pelechano V, Dündar F, Dasmeh P, Mittler G, Cadete FT, Ramírez F, Conrad T, Wei W, Raja S, Manke T, Luscombe NM, Steinmetz LM, Akhtar A

Perturbations of PIP3 signalling trigger a global remodelling of mRNA landscape and reveal a transcriptional feedback loop.

26464442 - 2015-10-16
Nucleic Acids Res 2015 Nov 16;43(20):9663-79
Kiselev VY, Juvin V, Malek M, Luscombe N, Hawkins P, Novère NL, Stephens L

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Missing link in epigenetics could explain conundrum of disease inheritance

08-07-2016 - All News

The process by which a mother’s diet during pregnancy can permanently affect her offspring’s attributes, such as weight, could be strongly influenced by genetic variation in an unexpected part of...

Epigenetic switch for obesity

08-02-2016 - All News

Obesity can sometimes be shut down It is well known that a predisposition to adiposity lies in our genes. A new study by researchers at the Max Planck Institute of Immunobiology...

Latest opportunities

Laboratory Research Technician - Tuesday, 26 July 2016
Postdoctoral Research Assistant in Epigenetics and Immuno-Oncology - Monday, 25 July 2016
ChroMe - An EU Marie Skłodowska-Curie Initial Training Network for PhD students - Monday, 11 July 2016
Postdoc at Humboldt University Berlin in chromatin biochemistry - Monday, 11 July 2016