Department of Physiology Development and Neuroscience at the University of Cambridge, UK
Environmental Modulation of Epigenetic States
Anne Ferguson-Smith is Professor of Developmental Genetics and Wellcome Senior Investigator at the University of Cambridge, Department of Physiology Development and Neuroscience. She studies genomic imprinting in development and disease and as a paradigm for analyzing the epigenetic control of genome function in mammals. In particular, her current research themes are: (a) mechanisms regulating the epigenetic programme in stem cells in vitro and in vivo, (b) functional integration of the genome and epigenome, and (c) modulation of the epigenetic control of gene dosage in normal and abnormal development and in physiological processes. Work in this latter category is supported in part by EpigeneSys and includes an exploration of the environmental modulation of epigenetic states in mouse models of the developmental origin of adult disease, and the mechanisms through which these may be transmitted to subsequent generations.
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Dr Marika Charalambous, PhD who is funded by EpigeneSys |  |
Dr Lizzie Radford, PhD whose work contributes to the WP |