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Systems biology

Epigenetics meets mathematics: Towards a quantitative understanding of chromatin biology

Philipp A. Steffen, João P. Fonseca, Leonie Ringrose, published online at BioEssays: 22 AUG 2012
This review explores the application of quantitative and mathematical approaches to mechanisms of epigenetic regulation
onlinelibrary.wiley link

 

Experimentalist Meets Theoretician: A Tale of Two Scientific Cultures

Supremely well-written story about how a small team of experimentalists and theoreticians collaborated to develop a theoretical model; why it is good for them to collaborate, and how these collaborations can be most productive.

by David G. Drubin and George Oster

link to abstract - link to pdf

 

GenoSpace emerges from stealth, launches new service

GenoSpace has launched a cloud-based software-as-a-service (SaaS) computing platform. According to Quankenbush, GenoSpace CEO, the storage and SaaS platform provides access to a variety of genomic and phenotypic data.
MHT link
 

Cell Systems Biology Issue: 18 March, 2011

In thinking about complexity, it's frequently invoked that the whole is greater than the sum of its parts. This notion serves as one of the motivating principles of systems biology, which seeks to understand the emergent properties of complex biological systems. Among many biologists, systems biology is also synonymous with the use of particular approaches, including high-throughput techniques, large-scale integration of datasets, and computational modeling to probe system behaviors.
Cell link

 


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