An ambitious EC-funded research initiative on epigenetics advancing towards systems biology
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Jonathan Houseley |
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The Babraham Institute, Cambridge, United Kingdom Modelling the influence of current epigenetic information on future actions
Histone modification patterns correlate with the transcriptional level of local genes, but clearly contain other information reflecting the history of the cell and affecting its responses to future stimuli. We are using conditioned behaviours of budding yeast to elucidate causes and predictive effects of histone modification. Specifically, we aim to quantify histone modification variations between cells grown in different environments, and model the effect of these epigenetic differences on future behavioural decisions. By doing so, we will derive predictive models for the influence of current epigenetic information on future gene expression patterns. |
News flash
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28.03.13
Scientists >> News
Residing in the physical heart of the cell, the nucleus has now fully shed its once one-dimensional reputation as the repository for genetic information and steady supplier of messages to the cytoplasm. This sea change…
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22.01.13
Scientists >> News
An open call for bilateral Franco-German projects in human epigenomics from the ANR-France has been announced! The deadline to submit a "declaration of intention" is March 29th, 2013. Click here for the announcement (in French).
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18.12.12
Scientists >> News
Edith Heard, named a Chair of the Collège de France in Epigenetics and Cellular Memory will be giving weekly lectures starting in February that, in the tradition of this great institution, are free for anyone to attend. Lectures (in French) are from 16-17:30…
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23.10.12
all videos >> Science clips for the public
Watch the Nobel Prize winner, Sir John Gurdon, speak about winning the prize and about his revolutionary work on nuclear reprogramming.
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