An ambitious EC-funded research initiative on epigenetics advancing towards systems biology
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Asifa Akhtar |
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Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany X chromosomal regulation  Over the last decade, the focus of the Akhtar laboratory has been to study the chromatin and epigenetic mechanisms underlying X-chromosome specific gene regulation using Drosophila dosage compensation as a model system. In Drosophila, dosage compensation is achieved by hyperactivation of the single X chromosome in males in comparison to the two female X chromosomes. They study how the dosage compensation complex, composed of RNA and proteins (The Male Specific Lethal (MSL) complex) gets targeted to the X chromosome and modulates transcriptional output. They are also interested in studying how nuclear organization influences X-chromosomal regulation. People involved in the lab:
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News flash
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28.03.13
Scientists >> News
Residing in the physical heart of the cell, the nucleus has now fully shed its once one-dimensional reputation as the repository for genetic information and steady supplier of messages to the cytoplasm. This sea change…
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22.01.13
Scientists >> News
An open call for bilateral Franco-German projects in human epigenomics from the ANR-France has been announced! The deadline to submit a "declaration of intention" is March 29th, 2013. Click here for the announcement (in French).
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18.12.12
Scientists >> News
Edith Heard, named a Chair of the Collège de France in Epigenetics and Cellular Memory will be giving weekly lectures starting in February that, in the tradition of this great institution, are free for anyone to attend. Lectures (in French) are from 16-17:30…
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23.10.12
all videos >> Science clips for the public
Watch the Nobel Prize winner, Sir John Gurdon, speak about winning the prize and about his revolutionary work on nuclear reprogramming.
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