Department of Physiology Development and Neuroscience at the University of Cambridge, UK
Environmental Modulation of Epigenetic States
Anne Ferguson-Smith is Professor of Developmental Genetics and Wellcome Senior Investigator at the University of Cambridge, Department of Physiology Development and Neuroscience. She studies genomic imprinting in development and disease and as a paradigm for analyzing the epigenetic control of genome function in mammals. In particular, her current research themes are: (a) mechanisms regulating the epigenetic programme in stem cells in vitro and in vivo, (b) functional integration of the genome and epigenome, and (c) modulation of the epigenetic control of gene dosage in normal and abnormal development and in physiological processes. Work in this latter category is supported in part by EpigeneSys and includes an exploration of the environmental modulation of epigenetic states in mouse models of the developmental origin of adult disease, and the mechanisms through which these may be transmitted to subsequent generations.
Residing in the physical heart of the cell, the nucleus has now fully shed its once one-dimensional reputation as the repository for genetic information and steady supplier of messages to the cytoplasm. This sea change…
An open call for bilateral Franco-German projects in human epigenomics from the ANR-France has been announced! The deadline to submit a "declaration of intention" is March 29th, 2013. Click here for the announcement (in French).
Edith Heard, named a Chair of the Collège de France in Epigenetics and Cellular Memory will be giving weekly lectures starting in February that, in the tradition of this great institution, are free for anyone to attend. Lectures (in French) are from 16-17:30…
Watch the Nobel Prize winner, Sir John Gurdon, speak about winning the prize and about his revolutionary work on nuclear reprogramming.