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Vardhman Rakyan

Blizard Institute, Barts and The London School of Medicine and Dentistry, London, UK

Signalling to the Epigenome

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vardhman rakyan

The overall goals of the lab are to understand the molecular basis of the non-genetically determined component of mammalian phenotypes and diseases. Within this context, we are particularly interested in 'epialleles' – loci at which the epigenetic state varies as a result of stochastic, genetic and/or environmental influences. We pursue several complementary lines of investigation that integrate molecular genomics, computational biology, mouse models, and human cohorts to understand the role of epialleles in complex phenotypes and diseases, transgenerational epigenetic inheritance, and environmental epigenomics.

 

 

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