Roger Foo |
Genome Institute of Singapore, Singapore Cardiac Epigenomics![]()
A major research focus of our lab is to understand the epigenome of the heart: how the environment, nutrients and metabolism might shape the cardiac epigenome, and equally how changes in the cardiac epigenome bring about changes in the function of the heart. We make use of heart samples from patients with heart failure as well and in vitro and in vivo experimental models of disease, and employ techniques of high-throughput sequencing and integrative genomics in order to map out what happens to the cardiac epigenome in health and disease. Our ultimate aim is to discover novel targets for heart failure therapy. Lab members:
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Residing in the physical heart of the cell, the nucleus has now fully shed its once one-dimensional reputation as the repository for genetic information and steady supplier of messages to the cytoplasm. This sea change…
An open call for bilateral Franco-German projects in human epigenomics from the ANR-France has been announced! The deadline to submit a "declaration of intention" is March 29th, 2013. Click here for the announcement (in French).
Edith Heard, named a Chair of the Collège de France in Epigenetics and Cellular Memory will be giving weekly lectures starting in February that, in the tradition of this great institution, are free for anyone to attend. Lectures (in French) are from 16-17:30…
Watch the Nobel Prize winner, Sir John Gurdon, speak about winning the prize and about his revolutionary work on nuclear reprogramming.