An ambitious EC-funded research initiative on epigenetics advancing towards systems biology

The structure and function of mammalian heterochromatin has been a major focus of our laboratory, since our discovery of the first histone lysine methyltransferases (KMTs). Currently, our research focuses on the epigenetic profiling of large chromosomal regions, analyzing the role of non-coding RNAs in heterochromatin formation, identifying all components for mammalian heterochromatin and dissecting signalling pathways to chromatin. As associated member we see many natural synergies with the research conducted within EpiGeneSys. In particular, we are convinced that our lines of research will significantly contribute to WP2 (Dynamics of Epigenetic Regulators) and WP4 (Signalling to the epigenome). In addition, we are also highly committed to support the training program for young scientists as well as the public education mission of EpiGeneSys.