An ambitious EC-funded research initiative on epigenetics advancing towards systems biology

Since its formation in May 2003, our group has focused its research efforts on understanding how epigenetic modifications and chromatin changes are established and, once in place, how they affect gene expression, cell differentiation and transformation. Gene expression and differentiation are mainly investigated in mouse embryonic stem cells, which can be induced to differentiate into embryoid bodies and neuronal precursors. Leukemia is the primary cancer model system studied in our lab, and we use either mouse models that recapitulate human leukemia or primary samples from human leukemic patients to investigate the links between epigenetic alterations and the tumorigenesis processes.

Luigi Aloia, Postdoctoral Fellow
Cecilia Julia Ballaré, Laboratory Technician
Malte Beringer, Postdoctoral Fellow
Santiago Demajo, Graduate Fellow
Arantxa Gutiérrez, Laboratory Technician
Payal Jain, Graduate Fellow
Lluís Morey, Postdoctoral Fellow
Paola Pisano, Graduate Fellow
Joana Ribeiro, Graduate Fellow
Alexandra Santanach, Graduate Fellow
Elisabeth Simboeck, Postdoctoral Fellow
Sophia Teichmann, Graduate Fellow