Advancing Epigenetics Towards Systems Biology

What is the difference between epigenetics and epigenomics?

In eukaryotic cells, the DNA is packaged within the nucleus in a structure called chromatin. This structure is a highly dynamic nucleoprotein complex that plays a central role in regulating how and when DNA is copied and transcribed into RNA. Thus chromatin states vary from cell type to cell type and along chromosomes. The epigenome refers to these states at the whole genome level. Typically, a multi-cellurar organism will be characterized by one genome, but by as many epigenomes as there are cell types.

Epigenetics encompasses all processes that lead to heritable changes in gene expression (during development or across generations) without changes in the DNA sequence itself. In eukaryotes, chromatin is at the heart of most epigenetic processes. Thus, the study of epigenetics often crosses that of epigenomes (epigenomics).

Wed, May 1st 2019- Sat, May 4th 2019

Epigenetics refers to heritable change in gene expression that does not involve changes to the underlying DNA sequence. At least three systems including DNA methylation, histone modifications and non-...

Mon, Jun 10th 2019- Tue, Jun 11th 2019

Following the success of the previous conferences, we are excited to announce that “7th International Conference on Hypertension & Healthcare” will be held during June 10-11, 2019 at the most beautif...

Mon, Jun 17th 2019- Wed, Jun 19th 2019

Being successful in the previous 3 conferences in the series, Cardiologists 2016 in Berlin, Germany, Cardiologists 2017 in Paris, France and Cardiologists 2018 in Barcelona, Spain, this year we are mo...

Mon, Jun 17th 2019- Tue, Jun 18th 2019

RNA modifications are ubiquitous in biology and present in all classes of cellular RNAs. Recent studies have shown that RNA modifications are critical to the processing and metabolism of different RNA...

LAST EVENTS

EpiGeneSys Final
Meeting in Paris

Thur. 11 February 2016 - Sat. 13 February 2016

More than 280 scientists attended the fifth Annual Meeting of EpiGeneSys. The conference kicked off with a talk by coordinator Geneviève Almouzni, Director of the Research Center at the Institut Curie, highlighting the achievements of the network over more than five years...

Maison des océans - Paris Read more

PAST EVENTS

The Non-Coding Genome ...

December 3-4 th, 2015

The last training workshop of the EpiGeneSys network

Hotel Mediterraneo - Rome, Italy Read more

Paris / TriRhena Chromatin Club

July 9th, 2015

...exciting talks and network with members of the Chromatin community!

... An EpiGeneSys TAB workshop

June 11st-12nd , 2015

... learn about current approaches to single cell epigenetics and to meet up and network with...

Montpellier, FranceRead more

Latest publications

2017-06-27

The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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2017-05-26

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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2017-04-30

The impact of rare and low-frequency genetic variants in common disease.

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