Advancing Epigenetics Towards Systems Biology

What is the difference between epigenetics and epigenomics?

In eukaryotic cells, the DNA is packaged within the nucleus in a structure called chromatin. This structure is a highly dynamic nucleoprotein complex that plays a central role in regulating how and when DNA is copied and transcribed into RNA. Thus chromatin states vary from cell type to cell type and along chromosomes. The epigenome refers to these states at the whole genome level. Typically, a multi-cellurar organism will be characterized by one genome, but by as many epigenomes as there are cell types.

Epigenetics encompasses all processes that lead to heritable changes in gene expression (during development or across generations) without changes in the DNA sequence itself. In eukaryotes, chromatin is at the heart of most epigenetic processes. Thus, the study of epigenetics often crosses that of epigenomes (epigenomics).

Mon, Nov 26th 2018- Tue, Nov 27th 2018

Epitranscriptomics 2018 invites all the participants from all over the world to attend International Conference on Epigenetics and Epitranscriptomics during November 26-27, 2018 Helsinki, Finland. The...

Tue, Nov 27th 2018- Fri, Nov 30th 2018

Cancer progression and development of resistance to treatment is an urgent medical problem. Epigenetic reprogramming is an integral component of lineage-specific transcriptional programmes and its pot...

Mon, Dec 3rd 2018- Tue, Dec 4th 2018

15th Edition of EuroScicon Conference on Advanced Stem Cells & Regenerative Medicine Dec 3-4, 2018, Valencia, Spain Stem Cells conferences 2018 | Regenerative Medicine conferences 2018 | Advanced Ste...

Wed, Dec 5th 2018- Fri, Dec 7th 2018

This is the 5th in a series of biennial conferences presenting cutting-edge research in the field of epigenetics. We are committed to create an exceptional environment for epigenetic research in Fre...


EpiGeneSys Final
Meeting in Paris

Thur. 11 February 2016 - Sat. 13 February 2016

More than 280 scientists attended the fifth Annual Meeting of EpiGeneSys. The conference kicked off with a talk by coordinator Geneviève Almouzni, Director of the Research Center at the Institut Curie, highlighting the achievements of the network over more than five years...

Maison des océans - Paris Read more


The Non-Coding Genome ...

December 3-4 th, 2015

The last training workshop of the EpiGeneSys network

Hotel Mediterraneo - Rome, Italy Read more

Paris / TriRhena Chromatin Club

July 9th, 2015

...exciting talks and network with members of the Chromatin community!

... An EpiGeneSys TAB workshop

June 11st-12nd , 2015

... learn about current approaches to single cell epigenetics and to meet up and network with...

Montpellier, FranceRead more

Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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The impact of rare and low-frequency genetic variants in common disease.

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