Advancing Epigenetics Towards Systems Biology

Epigenesys activities


Training workshop “Epigenomics as a Discovery Tool in Current Biology”

Thursday 19 September 2013 - Friday 20 September 2013

Location  : IMB - Mainz, Germany

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We are pleased to invite you to EpiGeneSys-IMB training workshop "Epigenomics as a Discovery Tool in Current Biology"

The event is organised by Vijay Tiwari with the support of the EpiGeneSys TAB

The workshop will:

  • provide an introduction to state-of-the-art experimental methods, computational analyses and applications of epigenomics technologies
  • feature three keynote lectures
  • include roundtable discussions on Gene Expression, Chromatin Modifications and Genome Organization as well as Proteomics in Epigenetics.

Background, focus of the workshop and importance to the field:

The epigenetic control of gene expression is increasingly recognized as a vital regulatory layer defining cell function and identity. New technological developments based upon next-generation sequencing are now enabling epigenetics researchers to address questions on a genome-wide basis and to elucidate general principles of epigenetic gene regulation. The next-generation sequencing approaches used range from mapping the DNA sequence (e.g. whole-genome-seq, exome sequencing) to profiling DNA methylation (e.g. bisulfite-seq) as well as chromatin accessibility (e.g. MNase-seq, DNase-seq, FAIRE-seq), chromatin organization (e.g. 4C-seq), the transcriptome (RNA-seq), transcription factor binding sites (ChIP-seq) and RNA-protein interactions (e.g. ChIRP-seq, CLIP-seq and variants). These approaches are generating systems-level data at an unprecedented scale and are therefore primed to fundamentally advance biomedical research. Through our workshop, we will provide participants with an introduction to state-of-the-art experimental methods, computational analyses and applications of epigenomics technologies.

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