Advancing Epigenetics Towards Systems Biology

PostDoc in Epigenetics and Chromatin Biology

Helmholtz Center Munich

Description

The newly established Institute of Functional Epigenetics at the Helmholtz Center Munich focuses on understanding how epigenetics impact on cellular function, reprogramming and metabolism. Specifically we unravel how chromatin mechanistically regulates these processes through changes in gene expression. Our research includes next generation sequencing (ChIPseq, RNAseq, CLIP etc.), single cell approaches, biochemistry and biophysical approaches as well as various developmental and cell biology systems. For details please visit: https://www.helmholtz-muenchen.de/ife

For a project on the interphase between chromatin biochemistry and epigenetics we are looking for a PostDoc with a strong research background, experience in the epigenetics or chromatin field and a proven publication record. The successful candidate will study novel chromatin modifying pathways, which we have recently identified, to address a central question in epigenetics: what are the mechanisms via which the cellular environment controls chromatin dynamics and thus gene expression programs and disease states ?

This project will involve a combination of in vitro and in vivo approaches, including different NGS (omics) techniques and their analysis as well the development of novel technologies to address mechanism in single cells and low-input material. It is designed to allow the applicant to play a major role in determining its direction.

Qualifications

Candidates for this position should have:
- PhD in biology or a related field
- Strong research background in chromatin research with a very good publication record
- Experience in at least two of the following fields is essential:
- chromatin biochemistry,
- ChIP seq and RNA seq techniques (including data analysis),
- single cell approaches
- histone modifications or variants
- Fluent written and spoken English

Salary

Our Offer
- An innovative and scientifically stimulating environment with excellent facilities and a vibrant epigenetics community
- The possibility to work on internationally competitive projects using state-of-the-art technologies
- Advanced interdisciplinary training opportunities
- Highly motivated research team

Application details

Please submit your application (motivation letter, detailed CV, copies of your certificates, and contact details of 2 referees) preferably as a single file per email to: This email address is being protected from spambots. You need JavaScript enabled to view it.
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