Advancing Epigenetics Towards Systems Biology


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Term Definition
the epigenome consists of chemical compounds that modify, or mark, the genome in a way that tells it what to do, where to do it, and when to do it. Different cells have different marks. These marks, which are not part of the DNA itself, can be passed on from cell to cell as cells divide, and from one generation to the next. Thus, these marks may constitute heritable epigenetic marks—but not necessarily—some of them may be lost during the cell cycle but they nevertheless provide a signature or flavor of chromatin that can correspond to its functional state.
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