Advancing Epigenetics Towards Systems Biology

CpG methylation

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CpG methylation
In mammals, methylation is found sparsely but globally, distributed in definite CpG sequences throughout the entire genome, with the exception of CpG islands, or certain stretches (approximately 1 kilobase in length) where high CpG content is found. The methylation of these sequences can lead to inappropriate gene silencing.
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