Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

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Group Leader:
Sarah Teichmann39 Publications.


Cellular crowding imposes global constraints on the chemistry and evolution of proteomes.

Proc Natl Acad Sci U S A 2012 Dec 11;109(50):20461-6

Levy ED, De S, Teichmann SA

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Uncovering the interplay between DNA sequence preferences of transcription factors and nucleosomes.

Cell Cycle 2012 Nov 19;11(24)

Teichmann SA, Wigge PA, Charoensawan V

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Probing the diverse landscape of protein flexibility and binding.

Curr Opin Struct Biol 2012 Oct;22(5):643-50

Marsh JA, Teichmann SA, Forman-Kay JD

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DNA sequence preferences of transcriptional activators correlate more strongly than repressors with nucleosomes.

Mol Cell 2012 Jul 27;47(2):183-92

Charoensawan V, Janga SC, Bulyk ML, Babu MM, Teichmann SA

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Evolution of oligomeric state through geometric coupling of protein interfaces.

Proc Natl Acad Sci U S A 2012 May 22;109(21):8127-32

Perica T, Chothia C, Teichmann SA

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The interface of protein structure, protein biophysics, and molecular evolution.

Protein Sci 2012 Mar 30;

Liberles DA, Teichmann SA, Bahar I, Bastolla U, Bloom J, Bornberg-Bauer E, Colwell LJ, de Koning AP, Dokholyan NV, Echave J, Elofsson A, Gerloff DL, Goldstein RA, Grahnen JA, Holder MT, Lakner C, Lartillot N, Lovell SC, Naylor G, Perica T, Pollock DD, Pupko T, Regan L, Roger A, Rubinstein N, Shakhnovich E, Sjölander K, Sunyaev S, Teufel AI, Thorne JL, Thornton JW, Weinreich DM, Whelan S

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Duel of the fates: the role of transcriptional circuits and noise in CD4+ cells.

Curr Opin Cell Biol 2012 Apr 10;

Hebenstreit D, Deonarine A, Babu MM, Teichmann SA

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Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs.

Cell Stem Cell 2012 Feb 3;10(2):157-70

Brookes E, de Santiago I, Hebenstreit D, Morris KJ, Carroll T, Xie SQ, Stock JK, Heidemann M, Eick D, Nozaki N, Kimura H, Ragoussis J, Teichmann SA, Pombo A

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How do you find transcription factors? Computational approaches to compile and annotate repertoires of regulators for any genome.

Methods Mol Biol 2012;786:3-19

Vaquerizas JM, Teichmann SA, Luscombe NM

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Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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The impact of rare and low-frequency genetic variants in common disease.

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