Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

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Group Leader:
Sarah Teichmann39 Publications.


Structure, Dynamics, Assembly, and Evolution of Protein Complexes.

Annu Rev Biochem 2014 Dec 8;

Marsh JA, Teichmann SA

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Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis.

Cell Rep 2014 May 22;7(4):1130-42

Mahata B, Zhang X, Kolodziejczyk AA, Proserpio V, Haim-Vilmovsky L, Taylor AE, Hebenstreit D, Dingler FA, Moignard V, Göttgens B, Arlt W, McKenzie AN, Teichmann SA

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Immunology meets genomics.

Brief Funct Genomics 2013 Nov;12(6):469-70

Teichmann SA

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Parallel dynamics and evolution: Protein conformational fluctuations and assembly reflect evolutionary changes in sequence and structure.

Bioessays 2013 Nov 25;

Marsh JA, Teichmann SA

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Accounting for technical noise in single-cell RNA-seq experiments.

Nat Methods 2013 Sep 22;

Brennecke P, Anders S, Kim JK, Kołodziejczyk AA, Zhang X, Proserpio V, Baying B, Benes V, Teichmann SA, Marioni JC, Heisler MG

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Evolution of protein structures and interactions from the perspective of residue contact networks.

Curr Opin Struct Biol 2013 Jul 25;

Zhang X, Perica T, Teichmann SA

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The Role of Salt Bridges, Charge Density, and Subunit Flexibility in Determining Disassembly Routes of Protein Complexes.

Structure 2013 Jul 9;

Hall Z, Hernández H, Marsh JA, Teichmann SA, Robinson CV

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Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia.

J Exp Med 2013 Jun 3;210(6):1137-51

Roberts EW, Deonarine A, Jones JO, Denton AE, Feig C, Lyons SK, Espeli M, Kraman M, McKenna B, Wells RJ, Zhao Q, Caballero OL, Larder R, Coll AP, O'Rahilly S, Brindle KM, Teichmann SA, Tuveson DA, Fearon DT

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Protein Complexes Are under Evolutionary Selection to Assemble via Ordered Pathways.

Cell 2013 Apr 11;153(2):461-70

Marsh JA, Hernández H, Hall Z, Ahnert SE, Perica T, Robinson CV, Teichmann SA

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Regulation of protein-protein binding by coupling between phosphorylation and intrinsic disorder: analysis of human protein complexes.

Mol Biosyst 2013 Jan 30;

Nishi H, Fong JH, Chang C, Teichmann SA, Panchenko AR

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Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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The impact of rare and low-frequency genetic variants in common disease.

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