Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

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Group Leader:
Jane Skok20 Publications.


4C-ker: A Method to Reproducibly Identify Genome-Wide Interactions Captured by 4C-Seq Experiments.

PLoS Comput Biol 2016 Mar;12(3):e1004780

Raviram R, Rocha PP, Müller CL, Miraldi ER, Badri S, Fu Y, Swanzey E, Proudhon C, Snetkova V, Bonneau R, Skok JA

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Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination.

J Exp Med 2016 Mar 7;213(3):303-12

Thomas-Claudepierre AS, Robert I, Rocha PP, Raviram R, Schiavo E, Heyer V, Bonneau R, Luo VM, Reddy JK, Borggrefe T, Skok JA, Reina-San-Martin B

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RAG Off-Target Activity Is in the Loop.

Trends Mol Med 2015 Dec;21(12):733-5

Blumenberg L, Skok JA

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Long-Range Regulation of V(D)J Recombination.

Adv Immunol 2015;128:123-82

Proudhon C, Hao B, Raviram R, Chaumeil J, Skok JA

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Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms.

J Exp Med 2015 Oct 19;212(11):1833-50

Mullenders J, Aranda-Orgilles B, Lhoumaud P, Keller M, Pae J, Wang K, Kayembe C, Rocha PP, Raviram R, Gong Y, Premsrirut PK, Tsirigos A, Bonneau R, Skok JA, Cimmino L, Hoehn D, Aifantis I

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Breaking TADs: insights into hierarchical genome organization.

Epigenomics 2015;7(4):523-6

Rocha PP, Raviram R, Bonneau R, Skok JA

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Transcription. CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation.

Science 2015 Feb 27;347(6225):1017-21

Narendra V, Rocha PP, An D, Raviram R, Skok JA, Mazzoni EO, Reinberg D

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VH replacement in primary immunoglobulin repertoire diversification.

Proc Natl Acad Sci U S A 2015 Jan 21;

Sun A, Novobrantseva TI, Coffre M, Hewitt SL, Jensen K, Skok JA, Rajewsky K, Koralov SB

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Taking a break from the lab: can it really be done?

Trends Cell Biol 2014 Dec;24(12):725-6

Skok JA

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Interpreting 4C-Seq data: how far can we go?

Epigenomics 2014 Oct;6(5):455-7

Raviram R, Rocha PP, Bonneau R, Skok JA

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Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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The impact of rare and low-frequency genetic variants in common disease.

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