Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

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Group Leader:
Rebecca Oakey8 Publications.


The Role of CCCTC-Binding Factor (CTCF) in Genomic Imprinting, Development, and Reproduction.

Biol Reprod 2014 Oct 8;

Franco MM, Prickett AR, Oakey RJ

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Developmental programming mediated by complementary roles of imprinted grb10 in mother and pup.

PLoS Biol 2014 Feb;12(2):e1001799

Cowley M, Garfield AS, Madon-Simon M, Charalambous M, Clarkson RW, Smalley MJ, Kendrick H, Isles AR, Parry AJ, Carney S, Oakey RJ, Heisler LK, Moorwood K, Wolf JB, Ward A

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Genomewide and parental allele-specific analysis of CTCF and cohesin DNA binding in mouse brain reveals a tissue-specific binding pattern and an association with imprinted differentially methylated regions.

Genome Res 2013 Jun 26;

Prickett AR, Barkas N, McCole RB, Hughes S, Amante SM, Schulz R, Oakey RJ

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The epigenetic regulator PLZF represses L1 retrotransposition in germ and progenitor cells.

EMBO J 2013 Jul 3;32(13):1941-52

Puszyk W, Down T, Grimwade D, Chomienne C, Oakey RJ, Solomon E, Guidez F

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Transposable elements re-wire and fine-tune the transcriptome.

PLoS Genet 2013 Jan;9(1):e1003234

Cowley M, Oakey RJ

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Resetting for the next generation.

Mol Cell 2012 Dec 28;48(6):819-21

Cowley M, Oakey RJ

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A survey of tissue-specific genomic imprinting in mammals.

Mol Genet Genomics 2012 Jul 21;

Prickett AR, Oakey RJ

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Epigenetic control of alternative mRNA processing at the imprinted Herc3/Nap1l5 locus.

Nucleic Acids Res 2012 Jul 11;

Cowley M, Wood AJ, Böhm S, Schulz R, Oakey RJ

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Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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The impact of rare and low-frequency genetic variants in common disease.

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