Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

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Group Leader:
Ingrid Grummt17 Publications.


lncRNA-Induced Nucleosome Repositioning Reinforces Transcriptional Repression of rRNA Genes upon Hypotonic Stress.

Cell Rep 2016 Mar 1;14(8):1876-82

Zhao Z, Dammert MA, Grummt I, Bierhoff H

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SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing.

Nat Commun 2016 Feb 12;7:10734

Chen S, Blank MF, Iyer A, Huang B, Wang L, Grummt I, Voit R

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LncRNA Khps1 Regulates Expression of the Proto-oncogene SPHK1 via Triplex-Mediated Changes in Chromatin Structure.

Mol Cell 2015 Nov 19;60(4):626-36

Postepska-Igielska A, Giwojna A, Gasri-Plotnitsky L, Schmitt N, Dold A, Ginsberg D, Grummt I

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Alu element-containing RNAs maintain nucleolar structure and function.

EMBO J 2015 Nov 12;34(22):2758-74

Caudron-Herger M, Pankert T, Seiler J, Németh A, Voit R, Grummt I, Rippe K

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Cooperative Action of Cdk1/cyclin B and SIRT1 Is Required for Mitotic Repression of rRNA Synthesis.

PLoS Genet 2015 May;11(5):e1005246

Voit R, Seiler J, Grummt I

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A novel RNA binding surface of the TAM domain of TIP5/BAZ2A mediates epigenetic regulation of rRNA genes.

Nucleic Acids Res 2015 May 26;43(10):5208-20

Anosova I, Melnik S, Tripsianes K, Kateb F, Grummt I, Sattler M

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Long Noncoding RNA TARID Directs Demethylation and Activation of the Tumor Suppressor TCF21 via GADD45A.

Mol Cell 2014 Jul 30;

Arab K, Park YJ, Lindroth AM, Schäfer A, Oakes C, Weichenhan D, Lukanova A, Lundin E, Risch A, Meister M, Dienemann H, Dyckhoff G, Herold-Mende C, Grummt I, Niehrs C, Plass C

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Quiescence-Induced LncRNAs Trigger H4K20 Trimethylation and Transcriptional Silencing.

Mol Cell 2014 Apr 23;

Bierhoff H, Dammert MA, Brocks D, Dambacher S, Schotta G, Grummt I

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NoRC silences rRNA genes, telomeres, and centromeres.

Cell Cycle 2014 Jan 13;13(4)

Postepska-Igielska A, Grummt I

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Repression of RNA Polymerase I upon Stress Is Caused by Inhibition of RNA-Dependent Deacetylation of PAF53 by SIRT7.

Mol Cell 2013 Nov 7;52(3):303-13

Chen S, Seiler J, Santiago-Reichelt M, Felbel K, Grummt I, Voit R

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Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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The impact of rare and low-frequency genetic variants in common disease.

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