Richard Festenstein7 Publications.
Continuous Histone Replacement by Hira Is Essential for Normal Transcriptional Regulation and De Novo DNA Methylation during Mouse Oogenesis.
Mol Cell 2015 Nov 19;60(4):611-25
Epigenetic and neurological effects and safety of high-dose nicotinamide in patients with Friedreich's ataxia: an exploratory, open-label, dose-escalation study.
Lancet 2014 Apr 30;
Tissue-dependent regulation of RNAP II dynamics: The missing link between transcription and trinucleotide repeat instability in diseases?
Transcription 2013 Aug 2;4(4)
Gene regulation and epigenetics in Friedreich's ataxia.
J Neurochem 2013 Aug;126 Suppl 1:21-42
Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by Vitamin B3.
Hum Mol Genet 2013 Mar 7;
Transcription Elongation and Tissue-Specific Somatic CAG Instability.
PLoS Genet 2012 Nov;8(11):e1003051
Context is everything: activators can also repress.
Nat Struct Mol Biol 2012 Oct 4;19(10):973-5