Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications


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Group Leader:
Eran Segal56 Publications.

2017

Bread Affects Clinical Parameters and Induces Gut Microbiome-Associated Personal Glycemic Responses.

Cell Metab 2017 Jun 6;25(6):1243-1253.e5

Korem T, Zeevi D, Zmora N, Weissbrod O, Bar N, Lotan-Pompan M, Avnit-Sagi T, Kosower N, Malka G, Rein M, Suez J, Goldberg BZ, Weinberger A, Levy AA, Elinav E, Segal E

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Involvement of a gut-retina axis in protection against dietary glycemia-induced age-related macular degeneration.

Proc Natl Acad Sci U S A 2017 May 15;

Rowan S, Jiang S, Korem T, Szymanski J, Chang ML, Szelog J, Cassalman C, Dasuri K, McGuire C, Nagai R, Du XL, Brownlee M, Rabbani N, Thornalley PJ, Baleja JD, Deik AA, Pierce KA, Scott JM, Clish CB, Smith DE, Weinberger A, Avnit-Sagi T, Lotan-Pompan M, Segal E, Taylor A

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Corrigendum: Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators.

Genome Res 2017 Mar;27(3):500

van Dijk D, Sharon E, Lotan-Pompan M, Weinberger A, Segal E, Carey LB

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Systematic Investigation of Transcription Factor Activity in the Context of Chromatin Using Massively Parallel Binding and Expression Assays.

Mol Cell 2017 Feb 16;65(4):604-617.e6

Levo M, Avnit-Sagi T, Lotan-Pompan M, Kalma Y, Weinberger A, Yakhini Z, Segal E

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2016

Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators.

Genome Res 2017 Jan;27(1):87-94

van Dijk D, Sharon E, Lotan-Pompan M, Weinberger A, Segal E, Carey LB

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Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations.

Cell 2016 Dec 1;167(6):1495-1510.e12

Thaiss CA, Levy M, Korem T, Dohnalová L, Shapiro H, Jaitin DA, David E, Winter DR, Gury-BenAri M, Tatirovsky E, Tuganbaev T, Federici S, Zmora N, Zeevi D, Dori-Bachash M, Pevsner-Fischer M, Kartvelishvily E, Brandis A, Harmelin A, Shibolet O, Halpern Z, Honda K, Amit I, Segal E, Elinav E

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Persistent microbiome alterations modulate the rate of post-dieting weight regain.

Nature 2016 Nov 24;

Thaiss CA, Itav S, Rothschild D, Meijer M, Levy M, Moresi C, Dohnalová L, Braverman S, Rozin S, Malitsky S, Dori-Bachash M, Kuperman Y, Biton I, Gertler A, Harmelin A, Shapiro H, Halpern Z, Aharoni A, Segal E, Elinav E

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Massively Parallel Interrogation of the Effects of Gene Expression Levels on Fitness.

Cell 2016 Aug 25;166(5):1282-1294.e18

Keren L, Hausser J, Lotan-Pompan M, Vainberg Slutskin I, Alisar H, Kaminski S, Weinberger A, Alon U, Milo R, Segal E

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Toward a Systematic Understanding of Translational Regulatory Elements in Human and Viruses.

RNA Biol 2016 Jul 21;:0

Weingarten-Gabbay S, Segal E

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A Minimalistic Resource Allocation Model to Explain Ubiquitous Increase in Protein Expression with Growth Rate.

PLoS One 2016;11(4):e0153344

Barenholz U, Keren L, Segal E, Milo R

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Latest publications

2017-06-27

The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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2017-05-26

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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2017-04-30

The impact of rare and low-frequency genetic variants in common disease.

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