Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications


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Group Leader:
Leonie Ringrose14 Publications.

2016

Linear ubiquitination by LUBEL has a role in Drosophila heat stress response.

EMBO Rep 2016 Oct 4;

Asaoka T, Almagro J, Ehrhardt C, Tsai I, Schleiffer A, Deszcz L, Junttila S, Ringrose L, Mechtler K, Kavirayani A, Gyenesei A, Hofmann K, Duchek P, Rittinger K, Ikeda F

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2015

Radical Sabbaticals.

Cell 2015 Nov 5;163(4):788-9

Clevers H, Firestein S, Ringrose L, Bernards R, Darwin KH, Vance RE

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Reconciling randomness and precision.

Nat Rev Mol Cell Biol 2015 Nov;16(11):642

Ringrose L

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The quest for mammalian Polycomb response elements: are we there yet?

Chromosoma 2015 Oct 9;

Bauer M, Trupke J, Ringrose L

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2014

A strand-specific switch in noncoding transcription switches the function of a Polycomb/Trithorax response element.

Nat Genet 2014 Aug 10;

Herzog VA, Lempradl A, Trupke J, Okulski H, Altmutter C, Ruge F, Boidol B, Kubicek S, Schmauss G, Aumayr K, Ruf M, Pospisilik A, Dimond A, Senergin HB, Vargas ML, Simon JA, Ringrose L

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What are memories made of? How Polycomb and Trithorax proteins mediate epigenetic memory.

Nat Rev Mol Cell Biol 2014 May;15(5):340-56

Steffen PA, Ringrose L

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2013

Quantitative in vivo analysis of chromatin binding of Polycomb and Trithorax group proteins reveals retention of ASH1 on mitotic chromatin.

Nucleic Acids Res 2013 Apr 10;

Steffen PA, Fonseca JP, Gänger C, Dworschak E, Kockmann T, Beisel C, Ringrose L

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2012

Epigenetics meets mathematics: Towards a quantitative understanding of chromatin biology.

Bioessays 2012 Oct;34(10):901-13

Steffen PA, Fonseca JP, Ringrose L

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First annual meeting of the EpiGeneSys Network of Excellence: Moving epigenetics towards systems biology.

Bioessays 2012 May 11;

Vandenberg A, Ringrose L

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In vivo Polycomb kinetics and mitotic chromatin binding distinguish stem cells from differentiated cells.

Genes Dev 2012 Apr 15;26(8):857-71

Fonseca JP, Steffen PA, Müller S, Lu J, Sawicka A, Seiser C, Ringrose L

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Latest publications

2017-06-27

The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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2017-05-26

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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2017-04-30

The impact of rare and low-frequency genetic variants in common disease.

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