Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

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Group Leader:
Wolf Reik67 Publications.


Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity.

Genome Biol 2016 Apr 18;17(1):72

Clark SJ, Lee HJ, Smallwood SA, Kelsey G, Reik W

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Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass.

Stem Cell Reports 2016 Apr 12;6(4):437-46

Guo G, von Meyenn F, Santos F, Chen Y, Reik W, Bertone P, Smith A, Nichols J

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Maternal DNA Methylation Regulates Early Trophoblast Development.

Dev Cell 2016 Jan 25;36(2):152-63

Branco MR, King M, Perez-Garcia V, Bogutz AB, Caley M, Fineberg E, Lefebvre L, Cook SJ, Dean W, Hemberger M, Reik W

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Germline and Pluripotent Stem Cells.

Cold Spring Harb Perspect Biol 2015 Nov 2;7(11)

Reik W, Surani MA

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Molecular signatures of plastic phenotypes in two eusocial insect species with simple societies.

Proc Natl Acad Sci U S A 2015 Nov 10;112(45):13970-5

Patalano S, Vlasova A, Wyatt C, Ewels P, Camara F, Ferreira PG, Asher CL, Jurkowski TP, Segonds-Pichon A, Bachman M, González-Navarrete I, Minoche AE, Krueger F, Lowy E, Marcet-Houben M, Rodriguez-Ales JL, Nascimento FS, Balasubramanian S, Gabaldon T, Tarver JE, Andrews S, Himmelbauer H, Hughes WO, Guigó R, Reik W, Sumner S

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5-Formylcytosine can be a stable DNA modification in mammals.

Nat Chem Biol 2015 Aug;11(8):555-7

Bachman M, Uribe-Lewis S, Yang X, Burgess HE, Iurlaro M, Reik W, Murrell A, Balasubramanian S

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Forget the Parents: Epigenetic Reprogramming in Human Germ Cells.

Cell 2015 Jun 4;161(6):1248-51

von Meyenn F, Reik W

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Data Resource Profile: Accessible Resource for Integrated Epigenomic Studies (ARIES).

Int J Epidemiol 2015 Aug;44(4):1181-90

Relton CL, Gaunt T, McArdle W, Ho K, Duggirala A, Shihab H, Woodward G, Lyttleton O, Evans DM, Reik W, Paul YL, Ficz G, Ozanne SE, Wipat A, Flanagan K, Lister A, Heijmans BT, Ring SM, Davey Smith G

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Prmt5: a guardian of the germline protects future generations.

EMBO J 2015 Feb 16;

Berrens RV, Reik W

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Global Reorganization of the Nuclear Landscape in Senescent Cells.

Cell Rep 2015 Jan 28;

Chandra T, Ewels PA, Schoenfelder S, Furlan-Magaril M, Wingett SW, Kirschner K, Thuret JY, Andrews S, Fraser P, Reik W

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Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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The impact of rare and low-frequency genetic variants in common disease.

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