Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

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Group Leader:
Andreas Ladurner30 Publications.


Modified Extended Trochanteric Osteotomy for the Treatment of Vancouver B2/B3 Periprosthetic Fractures of the Femur.

J Arthroplasty 2017 Mar 8;

Ladurner A, Zurmühle P, Zdravkovic V, Grob K

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sNASP and ASF1A function through both competitive and compatible modes of histone binding.

Nucleic Acids Res 2017 Jan 25;45(2):643-656

Bowman A, Koide A, Goodman JS, Colling ME, Zinne D, Koide S, Ladurner AG

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The poly(ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage.

Mol Biol Cell 2016 Dec 1;27(24):3791-3799

Sellou H, Lebeaupin T, Chapuis C, Smith R, Hegele A, Singh HR, Kozlowski M, Bultmann S, Ladurner AG, Timinszky G, Huet S

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Nick Your DNA, Mark Your Chromatin.

Mol Cell 2016 Oct 6;64(1):7-9

Nardozza AP, Ladurner AG

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CENPs and Sweet Nucleosomes Face the FACT.

Trends Biochem Sci 2016 Aug 4;

Murawska M, Ladurner AG

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Synthesis and Macrodomain Binding of Mono-ADP-Ribosylated Peptides.

Angew Chem Int Ed Engl 2016 Jul 28;

Kistemaker HA, Nardozza AP, Overkleeft HS, van der Marel GA, Ladurner AG, Filippov DV

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The Metabolic Impact on Histone Acetylation and Transcription in Ageing.

Trends Biochem Sci 2016 Jun 6;

Peleg S, Feller C, Ladurner AG, Imhof A

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The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1.

Cell Rep 2016 Feb 9;14(5):1156-68

Dell'Orso S, Wang AH, Shih HY, Saso K, Berghella L, Gutierrez-Cruz G, Ladurner AG, O'Shea JJ, Sartorelli V, Zare H

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Life span extension by targeting a link between metabolism and histone acetylation in Drosophila.

EMBO Rep 2016 Jan 18;

Peleg S, Feller C, Forne I, Schiller E, Sévin DC, Schauer T, Regnard C, Straub T, Prestel M, Klima C, Schmitt Nogueira M, Becker L, Klopstock T, Sauer U, Becker PB, Imhof A, Ladurner AG

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The histone chaperone sNASP binds a conserved peptide motif within the globular core of histone H3 through its TPR repeats.

Nucleic Acids Res 2015 Dec 15;

Bowman A, Lercher L, Singh HR, Zinne D, Timinszky G, Carlomagno T, Ladurner AG

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Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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The impact of rare and low-frequency genetic variants in common disease.

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