Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

Information is retrieved from


Back to the index page

Group Leader:
Edith Heard63 Publications.


X chromosome inactivation: new players in the initiation of gene silencing.

F1000Res 2017;6

Pinheiro I, Heard E

View on PubMed

Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells.

Nat Genet 2017 Mar;49(3):377-386

Xu J, Carter AC, Gendrel AV, Attia M, Loftus J, Greenleaf WJ, Tibshirani R, Heard E, Chang HY

View on PubMed


XACT Noncoding RNA Competes with XIST in the Control of X Chromosome Activity during Human Early Development.

Cell Stem Cell 2016 Dec 1;

Vallot C, Patrat C, Collier AJ, Huret C, Casanova M, Liyakat Ali TM, Tosolini M, Frydman N, Heard E, Rugg-Gunn PJ, Rougeulle C

View on PubMed

Efficient and versatile CRISPR engineering of human neurons in culture to model neurological disorders.

Wellcome Open Res 2016 Nov 15;1:13

Shah RR, Cholewa-Waclaw J, Davies FC, Paton KM, Chaligne R, Heard E, Abbott CM, Bird AP

View on PubMed

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2.

Nat Commun 2016 Nov 28;7:13661

Cooper S, Grijzenhout A, Underwood E, Ancelin K, Zhang T, Nesterova TB, Anil-Kirmizitas B, Bassett A, Kooistra SM, Agger K, Helin K, Heard E, Brockdorff N

View on PubMed

3D solutions to complex gene regulation.

Nat Rev Mol Cell Biol 2016 Nov 21;17(12):739

Heard E

View on PubMed

Closing the loop: 3C versus DNA FISH.

Genome Biol 2016 Oct 19;17(1):215

Giorgetti L, Heard E

View on PubMed

Transcriptional Analysis by Nascent RNA FISH of In Vivo Trophoblast Giant Cells or In Vitro Short-term Cultures of Ectoplacental Cone Explants.

J Vis Exp 2016 Aug 31;(114)

Corbel C, Heard E

View on PubMed

Genomes of Ellobius species provide insight into the evolutionary dynamics of mammalian sex chromosomes.

Genome Res 2016 Sep;26(9):1202-10

Mulugeta E, Wassenaar E, Sleddens-Linkels E, van IJcken WF, Heard E, Grootegoed JA, Just W, Gribnau J, Baarends WM

View on PubMed

Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming.

Nat Commun 2016 Aug 10;7:12354

Cantone I, Bagci H, Dormann D, Dharmalingam G, Nesterova T, Brockdorff N, Rougeulle C, Vallot C, Heard E, Chaligne R, Merkenschlager M, Fisher AG

View on PubMed

Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

Read more

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

Read more

The impact of rare and low-frequency genetic variants in common disease.

Read more