Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

Information is retrieved from


Back to the index page

Group Leader:
Pierre Ferrier13 Publications.


Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells.

Science 2016 Jan 21;

Soucie EL, Weng Z, Geirsdóttir L, Molawi K, Maurizio J, Fenouil R, Mossadegh-Keller N, Gimenez G, VanHille L, Beniazza M, Favret J, Berruyer C, Perrin P, Hacohen N, Andrau JC, Ferrier P, Dubreuil P, Sidow A, Sieweke MH

View on PubMed


Dynamic recruitment of Ets1 to both nucleosome-occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation.

Nucleic Acids Res 2015 Dec 15;

Cauchy P, Maqbool MA, Zacarias-Cabeza J, Vanhille L, Koch F, Fenouil R, Gut M, Gut I, Santana MA, Griffon A, Imbert J, Moraes-Cabé C, Bories JC, Ferrier P, Spicuglia S, Andrau JC

View on PubMed

Long-Range Control of V(D)J Recombination & Allelic Exclusion: Modeling Views.

Adv Immunol 2015;128:363-413

Outters P, Jaeger S, Zaarour N, Ferrier P

View on PubMed

Transcription-Dependent Generation of a Specialized Chromatin Structure at the TCRβ Locus.

J Immunol 2015 Mar 2;

Zacarías-Cabeza J, Belhocine M, Vanhille L, Cauchy P, Koch F, Pekowska A, Fenouil R, Bergon A, Gut M, Gut I, Eick D, Imbert J, Ferrier P, Andrau JC, Spicuglia S

View on PubMed


Experimental detection of long-distance interactions between biomolecules through their diffusion behavior: Numerical study.

Phys Rev E Stat Nonlin Soft Matter Phys 2014 Aug;90(2-1):022703

Nardecchia I, Spinelli L, Preto J, Gori M, Floriani E, Jaeger S, Ferrier P, Pettini M

View on PubMed


Epigenetic aspects of lymphocyte antigen receptor gene rearrangement or 'when stochasticity completes randomness'

Immunology 2012 Dec 26;

Jaeger S, Fernandez B, Ferrier P

View on PubMed


Experimental assessment of the contribution of electrodynamic interactions to long-distance recruitment of biomolecular partners: Theoretical basis.

Phys Rev E Stat Nonlin Soft Matter Phys 2012 Apr;85(4-1):041904

Preto J, Floriani E, Nardecchia I, Ferrier P, Pettini M

View on PubMed

Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation.

EMBO J 2012 May 1;31(12):2784-97

Hintermair C, Heidemann M, Koch F, Descostes N, Gut M, Gut I, Fenouil R, Ferrier P, Flatley A, Kremmer E, Chapman RD, Andrau JC, Eick D

View on PubMed

TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression.

Cancer Cell 2012 Apr 17;21(4):563-76

Dadi S, Le Noir S, Payet-Bornet D, Lhermitte L, Zacarias-Cabeza J, Bergeron J, Villarèse P, Vachez E, Dik WA, Millien C, Radford I, Verhoeyen E, Cosset FL, Petit A, Ifrah N, Dombret H, Hermine O, Spicuglia S, Langerak AW, Macintyre EA, Nadel B, Ferrier P, Asnafi V

View on PubMed


Characterisation of genome-wide PLZF/RARA target genes.

PLoS One 2011;6(9):e24176

Spicuglia S, Vincent-Fabert C, Benoukraf T, Tibéri G, Saurin AJ, Zacarias-Cabeza J, Grimwade D, Mills K, Calmels B, Bertucci F, Sieweke M, Ferrier P, Duprez E

View on PubMed

Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

Read more

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

Read more

The impact of rare and low-frequency genetic variants in common disease.

Read more