Fabrizio D'Adda di Fagagna19 Publications.
DICER, DROSHA and DNA damage-response RNAs are necessary for the secondary recruitment of DNA damage response factors.
J Cell Sci 2016 Feb 16;
Human nuclear ARGONAUTE 2 interacts in vivo only with small RNAs and not with DNA.
Cell Cycle 2015 Jul 3;14(13):2001-2
Notch is a direct negative regulator of the DNA-damage response.
Nat Struct Mol Biol 2015 May;22(5):417-24
Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion.
EMBO J 2015 Mar 27;
RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA.
EMBO Rep 2014 Dec 19;
Stable Cellular Senescence Is Associated with Persistent DDR Activation.
PLoS One 2014;9(10):e110969
Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing.
Curr Opin Genet Dev 2014 Aug 4;26C:89-95
Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication.
Nat Commun 2014 Apr 14;5:3649
DNA Damage in Mammalian Neural Stem Cells Leads to Astrocytic Differentiation Mediated by BMP2 Signaling through JAK-STAT.
Stem Cell Reports 2013 Jul 25;1(2):123-38
Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer.
Nat Rev Cancer 2012 Oct;12(10):709-20