Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

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Group Leader:
Caroline Hill21 Publications.


Distinct modes of SMAD2 chromatin binding and remodeling shape the transcriptional response to NODAL/Activin signaling.

Elife 2017 Feb 13;6

Coda DM, Gaarenstroom T, East P, Patel H, Miller DS, Lobley A, Matthews N, Stewart A, Hill CS

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Calreticulin is a secreted BMP antagonist, expressed in Hensen's node during neural induction.

Dev Biol 2016 Dec 2;

De Almeida I, Oliveira NM, Randall RA, Hill CS, McCoy JM, Stern CD

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Transcriptional Control by the SMADs.

Cold Spring Harb Perspect Biol 2016 Jul 22;

Hill CS

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Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization.

Cell Rep 2015 Dec 22;13(11):2456-69

Del Pozo Martin Y, Park D, Ramachandran A, Ombrato L, Calvo F, Chakravarty P, Spencer-Dene B, Derzsi S, Hill CS, Sahai E, Malanchi I

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A Temporal Window for Signal Activation Dictates the Dimensions of a Nodal Signaling Domain.

Dev Cell 2015 Oct 26;35(2):175-85

van Boxtel AL, Chesebro JE, Heliot C, Ramel MC, Stone RK, Hill CS

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Annual meeting of the EpiGeneSys Network of Excellence - Advancing epigenetics towards systems biology.

Bioessays 2015 Mar 16;

Houseley J, Hill CS, Rugg-Gunn PJ

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Response to comment on "Controlling long-term signaling: Receptor dynamics determine attenuation and refractory behavior of the TGF-β pathway"-Smad2/3 activity does not predict the dynamics of transcription.

Sci Signal 2014 Sep 23;7(344):lc2

Vizán P, J Miller DS, Schmierer B, Hill CS

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TGF-β signaling to chromatin: How Smads regulate transcription during self-renewal and differentiation.

Semin Cell Dev Biol 2014 Feb 4;

Gaarenstroom T, Hill CS

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Controlling Long-Term Signaling: Receptor Dynamics Determine Attenuation and Refractory Behavior of the TGF-β Pathway.

Sci Signal 2013 Dec 10;6(305):ra106

Vizán P, Miller DS, Gori I, Das D, Schmierer B, Hill CS

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A BMP regulatory network controls ectodermal cell fate decisions at the neural plate border.

Development 2013 Oct 2;

Reichert S, Randall RA, Hill CS

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Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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The impact of rare and low-frequency genetic variants in common disease.

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