Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications


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Group Leader:
Robin Allshire28 Publications.

2017

Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution.

EMBO Rep 2017 May 12;

Davis MP, Carrieri C, Saini HK, van Dongen S, Leonardi T, Bussotti G, Monahan JM, Auchynnikava T, Bitetti A, Rappsilber J, Allshire RC, Shkumatava A, O'Carroll D, Enright AJ

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2016

Transcription-coupled changes to chromatin underpin gene silencing by transcriptional interference.

Nucleic Acids Res 2016 Sep 8;

Ard R, Allshire RC

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Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein.

PLoS Genet 2016 Jun;12(6):e1006095

Much C, Auchynnikava T, Pavlinic D, Buness A, Rappsilber J, Benes V, Allshire R, O'Carroll D

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Centromere localization and function of Mis18 requires Yippee-like domain-mediated oligomerization.

EMBO Rep 2016 Feb 26;

Subramanian L, Medina-Pritchard B, Barton R, Spiller F, Kulasegaran-Shylini R, Radaviciute G, Allshire RC, Arockia Jeyaprakash A

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2015

Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organisation.

EMBO Rep 2016 Jan;17(1):79-93

Gal C, Murton HE, Subramanian L, Whale AJ, Moore KM, Paszkiewicz K, Codlin S, Bähler J, Creamer KM, Partridge JF, Allshire RC, Kent NA, Whitehall SK

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Epigenetic Regulation of Chromatin States in Schizosaccharomyces pombe.

Cold Spring Harb Perspect Biol 2015 Jul 1;7(7):a018770

Allshire RC, Ekwall K

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Epigenetics. Restricted epigenetic inheritance of H3K9 methylation.

Science 2015 Apr 3;348(6230):132-5

Audergon PN, Catania S, Kagansky A, Tong P, Shukla M, Pidoux AL, Allshire RC

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A nucleosome turnover map reveals that the stability of histone H4 Lys20 methylation depends on histone recycling in transcribed chromatin.

Genome Res 2015 Mar 16;

Svensson JP, Shukla M, Menendez-Benito V, Norman-Axelsson U, Audergon P, Sinha I, Tanny JC, Allshire RC, Ekwall K

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Sequence Features and Transcriptional Stalling within Centromere DNA Promote Establishment of CENP-A Chromatin.

PLoS Genet 2015 Mar;11(3):e1004986

Catania S, Pidoux AL, Allshire RC

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2014

Pan-Species Small Molecule Disruptors of Heterochromatin-Mediated Transcriptional Gene Silencing.

Mol Cell Biol 2014 Dec 8;

Castonguay E, White SA, Kagansky A, St-Cyr DJ, Castillo AG, Brugger C, White R, Bonilla C, Spitzer M, Earnshaw WC, Schalch T, Ekwall K, Tyers M, Allshire RC

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Latest publications

2017-06-27

The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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2017-05-26

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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2017-04-30

The impact of rare and low-frequency genetic variants in common disease.

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