Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

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Group Leader:
William Ritchie4 Publications.


A dynamic intron retention program in the mammalian megakaryocyte and erythrocyte lineages.

Blood 2016 Mar 9;

Edwards CR, Ritchie W, Wong JJ, Schmitz U, Middleton R, An X, Mohandas N, Rasko JE, Blobel GA

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RBM3 regulates temperature sensitive miR-142-5p and miR-143 (thermomiRs), which target immune genes and control fever.

Nucleic Acids Res 2016 Jan 28;

Wong JJ, Au AY, Gao D, Pinello N, Kwok CT, Thoeng A, Lau KA, Gordon JE, Schmitz U, Feng Y, Nguyen TV, Middleton R, Bailey CG, Holst J, Rasko JE, Ritchie W

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Real-time tracking of cell cycle progression during CD8(+) effector and memory T-cell differentiation.

Nat Commun 2015 Feb 24;6:6301

Kinjyo I, Qin J, Tan SY, Wellard CJ, Mrass P, Ritchie W, Doi A, Cavanagh LL, Tomura M, Sakaue-Sawano A, Kanagawa O, Miyawaki A, Hodgkin PD, Weninger W

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Targeting ASCT2-Mediated Glutamine Uptake Blocks Prostate Cancer Growth and Tumour Development.

J Pathol 2015 Feb 19;

Wang Q, Hardie RA, Hoy AJ, van Geldermalsen M, Gao D, Fazli L, Sadowski MC, Balaban S, Schreuder M, Nagarajah R, Wong JJ, Metierre C, Pinello N, Otte NJ, Lehman ML, Gleave M, Nelson CC, Bailey CG, Ritchie W, Rasko JE, Holst J

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Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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The impact of rare and low-frequency genetic variants in common disease.

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