Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications


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Group Leader:
John Marioni23 Publications.

2016

Codon-Driven Translational Efficiency Is Stable across Diverse Mammalian Cell States.

PLoS Genet 2016 May;12(5):e1006024

Rudolph KL, Schmitt BM, Villar D, White RJ, Marioni JC, Kutter C, Odom DT

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Pooling across cells to normalize single-cell RNA sequencing data with many zero counts.

Genome Biol 2016 Apr 27;17(1):75

L Lun AT, Bach K, Marioni JC

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Beyond comparisons of means: understanding changes in gene expression at the single-cell level.

Genome Biol 2016 Apr 15;17(1):70

Vallejos CA, Richardson S, Marioni JC

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Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos.

Cell 2016 Mar 24;165(1):61-74

Goolam M, Scialdone A, Graham SJ, Macaulay IC, Jedrusik A, Hupalowska A, Voet T, Marioni JC, Zernicka-Goetz M

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Classification of low quality cells from single-cell RNA-seq data.

Genome Biol 2016 Feb 17;17(1):29

Ilicic T, Kim JK, Kolodziejczyk AA, Bagger FO, McCarthy DJ, Marioni JC, Teichmann SA

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Corrigendum: Characterizing noise structure in single-cell RNA-seq distinguishes genuine from technical stochastic allelic expression.

Nat Commun 2016 Jan 11;7:10415

Kim JK, Kolodziejczyk AA, Ilicic T, Teichmann SA, Marioni JC

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2015

Hierarchical deconstruction of mouse olfactory sensory neurons: from whole mucosa to single-cell RNA-seq.

Sci Rep 2015 Dec 16;5:18178

Saraiva LR, Ibarra-Soria X, Khan M, Omura M, Scialdone A, Mombaerts P, Marioni JC, Logan DW

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Characterizing noise structure in single-cell RNA-seq distinguishes genuine from technical stochastic allelic expression.

Nat Commun 2015 Oct 22;6:8687

Kim JK, Kolodziejczyk AA, Illicic T, Teichmann SA, Marioni JC

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Single Cell RNA-Sequencing of Pluripotent States Unlocks Modular Transcriptional Variation.

Cell Stem Cell 2015 Oct 1;17(4):471-85

Kolodziejczyk AA, Kim JK, Tsang JC, Ilicic T, Henriksson J, Natarajan KN, Tuck AC, Gao X, Bühler M, Liu P, Marioni JC, Teichmann SA

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Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5' splice site strength.

Genome Biol 2015 Sep 21;16(1):201

Wickramasinghe VO, Gonzàlez-Porta M, Perera D, Bartolozzi AR, Sibley CR, Hallegger M, Ule J, Marioni JC, Venkitaraman AR

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Latest publications

2017-06-27

The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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2017-05-26

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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2017-04-30

The impact of rare and low-frequency genetic variants in common disease.

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