Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

Information is retrieved from


Back to the index page

Group Leader:
Laura Riva9 Publications.


In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype.

Cancer Discov 2016 May 13;

Bossi D, Cicalese A, Dellino GI, Luzi L, Riva L, D'Alesio C, Diaferia GR, Carugo A, Cavallaro E, Piccioni R, Barberis M, Mazzarol G, Testori A, Punzi S, Pallavicini I, Tosti G, Giacó L, Melloni G, Heffernan TP, Natoli G, Draetta GF, Minucci S, Pelicci P, Lanfrancone L

View on PubMed

LowMACA: exploiting protein family analysis for the identification of rare driver mutations in cancer.

BMC Bioinformatics 2016 Feb 9;17(1):80

Melloni GE, de Pretis S, Riva L, Pelizzola M, Céol A, Costanza J, Müller H, Zammataro L

View on PubMed


Peak shape clustering reveals biological insights.

BMC Bioinformatics 2015 Oct 28;16:349

Cremona MA, Sangalli LM, Vantini S, Dellino GI, Pelicci PG, Secchi P, Riva L

View on PubMed

INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments.

Bioinformatics 2015 May 7;

de Pretis S, Kress T, Morelli MJ, Melloni GE, Riva L, Amati B, Pelizzola M

View on PubMed

Whole exome sequencing identifies driver mutations in asymptomatic computed tomography-detected lung cancers with normal karyotype.

Cancer Genet 2015 Apr;208(4):152-5

Belloni E, Veronesi G, Rotta L, Volorio S, Sardella D, Bernard L, Pece S, Di Fiore PP, Fumagalli C, Barberis M, Spaggiari L, Pelicci PG, Riva L

View on PubMed

DOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes.

Genome Med 2014;6(6):44

Melloni GE, Ogier AG, de Pretis S, Mazzarella L, Pelizzola M, Pelicci PG, Riva L

View on PubMed


Hepatitis C virus life cycle and lipid metabolism.

Biology (Basel) 2014 Dec 15;3(4):892-921

Popescu CI, Riva L, Vlaicu O, Farhat R, Rouillé Y, Dubuisson J

View on PubMed

Deletion of the ORF9p acidic cluster impairs the nuclear egress of Varicella-zoster virus capsids.

J Virol 2014 Dec 3;

Riva L, Thiry M, Lebrun M, L'homme L, Piette J, Sadzot-Delvaux C

View on PubMed

The Genomic and Epigenomic Landscapes of AML.

Semin Hematol 2014 Oct;51(4):259-72

Mazzarella L, Riva L, Luzi L, Ronchini C, Pelicci PG

View on PubMed

Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

Read more

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

Read more

The impact of rare and low-frequency genetic variants in common disease.

Read more