Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

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Group Leader:
Ana Losada8 Publications.


Bub1 targeting to centromeres is sufficient for Sgo1 recruitment in the absence of kinetochores.

Chromosoma 2016 Apr 26;

Williams SJ, Abrieu A, Losada A

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Sororin loads to the synaptonemal complex central region independently of meiotic cohesin complexes.

EMBO Rep 2016 Mar 7;

Gómez R, Felipe-Medina N, Ruiz-Torres M, Berenguer I, Viera A, Pérez S, Barbero JL, Llano E, Fukuda T, Alsheimer M, Pendás AM, Losada A, Suja JA

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The contribution of cohesin-SA1 to gene expression and chromatin architecture in two murine tissues.

Nucleic Acids Res 2015 Mar 3;

Cuadrado A, Remeseiro S, Graña O, Pisano DG, Losada A

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The distinct functions of CENP-C and CENP-T/W in centromere propagation and function in Xenopus egg extracts.

Nucleus 2015 Jan 8;:0

Krizaic I, Williams SJ, Sánchez P, Rodríguez-Corsino M, Stukenberg T, Losada A

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Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres.

EMBO J 2013 Oct 18;

Carretero M, Ruiz-Torres M, Rodríguez-Corsino M, Barthelemy I, Losada A

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Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy.

Nat Genet 2013 Oct 13;

Balbás-Martínez C, Sagrera A, Carrillo-de-Santa-Pau E, Earl J, Márquez M, Vazquez M, Lapi E, Castro-Giner F, Beltran S, Bayés M, Carrato A, Cigudosa JC, Domínguez O, Gut M, Herranz J, Juanpere N, Kogevinas M, Langa X, López-Knowles E, Lorente JA, Lloreta J, Pisano DG, Richart L, Rico D, Salgado RN, Tardón A, Chanock S, Heath S, Valencia A, Losada A, Gut I, Malats N, Real FX

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Cohesin in development and disease.

Development 2013 Sep;140(18):3715-8

Remeseiro S, Cuadrado A, Losada A

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Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome.

Biochim Biophys Acta 2013 Aug 3;

Remeseiro S, Cuadrado A, Kawauchi S, Calof AL, Lander AD, Losada A

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Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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The impact of rare and low-frequency genetic variants in common disease.

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