Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

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Group Leader:
Luisa Pinto10 Publications.


A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide.

Oncotarget 2015 Feb 20;

Pojo M, Gonçalves CS, Xavier-Magalhães A, Oliveira AI, Gonçalves T, Correia S, Rodrigues AJ, Costa S, Pinto L, Pinto AA, Lopes JM, Reis RM, Rocha M, Sousa N, Costa BM

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Secretome of Mesenchymal Progenitors from the Umbilical Cord Acts as Modulator of Neural/Glial Proliferation and Differentiation.

Stem Cell Rev 2014 Nov 25;

Teixeira FG, Carvalho MM, Neves-Carvalho A, Panchalingam KM, Behie LA, Pinto L, Sousa N, Salgado AJ

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The effects of chronic stress on hippocampal adult neurogenesis and dendritic plasticity are reversed by selective MAO-A inhibition.

J Psychopharmacol 2014 Oct 14;

Morais M, Santos PA, Mateus-Pinheiro A, Patrício P, Pinto L, Sousa N, Pedroso P, Almeida S, Filipe A, Bessa JM

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Restless legs syndrome in pregnancy: a frequent underdiagnosed disorder.

Acta Med Port 2014 Jul-Aug;27(4):532

Policiano C, Nunes C, Pinto P, Centeno M, Pinto L, Graça LM

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Differential and Converging Molecular Mechanisms of Antidepressants' Action in the Hippocampal Dentate Gyrus.

Neuropsychopharmacology 2014 Jul 18;

Patrício P, Mateus-Pinheiro A, Irmler M, Alves ND, Machado-Santos AR, Morais M, Correia JS, Korostynski M, Piechota M, Stoffel R, Beckers J, Bessa JM, Almeida OF, Sousa N, Pinto L

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Incarcerated gravid uterus: early manual reduction vs. late spontaneous resolution.

Eur J Obstet Gynecol Reprod Biol 2014 Jun 2;

Policiano C, Araújo C, Santo S, Centeno M, Pinto L

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The Sweet Drive Test: refining phenotypic characterization of anhedonic behavior in rodents.

Front Behav Neurosci 2014;8:74

Mateus-Pinheiro A, Patrício P, Alves ND, Machado-Santos AR, Morais M, Bessa JM, Sousa N, Pinto L

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Glucocorticoid programing of the mesopontine cholinergic system.

Front Endocrinol (Lausanne) 2013 Dec 13;4:190

Borges S, Coimbra B, Soares-Cunha C, Ventura-Silva AP, Pinto L, Carvalho MM, Pêgo JM, Rodrigues AJ, Sousa N

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Development and Characterization of a PHB-HV-based 3D Scaffold for a Tissue Engineering and Cell-therapy Combinatorial Approach for Spinal Cord Injury Regeneration.

Macromol Biosci 2013 Aug 22;

Ribeiro-Samy S, Silva NA, Correlo VM, Fraga JS, Pinto L, Teixeira-Castro A, Leite-Almeida H, Almeida A, Gimble JM, Sousa N, Salgado AJ, Reis RL

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Re-cycling Paradigms: Cell Cycle Regulation in Adult Hippocampal Neurogenesis and Implications for Depression.

Mol Neurobiol 2013 Aug;48(1):84-96

Patrício P, Mateus-Pinheiro A, Sousa N, Pinto L

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Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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The impact of rare and low-frequency genetic variants in common disease.

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