Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications


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Group Leader:
Michael O. Hottiger23 Publications.

2016

SnapShot: ADP-Ribosylation Signaling.

Mol Cell 2016 May 5;62(3):472

Hottiger MO

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Absent in Melanoma 2 (AIM2) limits pro-inflammatory cytokine transcription in cardiomyocytes by inhibiting STAT1 phosphorylation.

Mol Immunol 2016 May 2;74:47-58

Furrer A, Hottiger MO, Valaperti A

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Regulation of bone morphogenetic protein signaling by ADP-ribosylation.

J Biol Chem 2016 Apr 21;

Watanabe Y, Papoutsoglou P, Maturi V, Tsubakihara Y, Hottiger MO, Heldin CH, Moustakas A

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Poly(ADP-ribosyl)ation of methyl CpG binding protein 2 regulates chromatin structure.

J Biol Chem 2016 Apr 22;291(17):9382

Becker A, Zhang P, Allmann L, Meilinger D, Bertulat B, Eck D, Hofstaetter M, Bartolomei G, Hottiger MO, Schreiber V, Leonhardt H, Cardoso MC

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A continuous sirtuin activity assay without any coupling to enzymatic or chemical reactions.

Sci Rep 2016 Mar 4;6:22643

Schuster S, Roessler C, Meleshin M, Zimmermann P, Simic Z, Kambach C, Schiene-Fischer C, Steegborn C, Hottiger MO, Schutkowski M

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ARTD1 regulates osteoclastogenesis and bone homeostasis by dampening NF-κB-dependent transcription of IL-1β.

Sci Rep 2016 Feb 17;6:21131

Robaszkiewicz A, Qu C, Wisnik E, Ploszaj T, Mirsaidi A, Kunze FA, Richards PJ, Cinelli P, Mbalaviele G, Hottiger MO

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Analysis of Chromatin ADP-Ribosylation at the Genome-wide Level and at Specific Loci by ADPr-ChAP.

Mol Cell 2016 Feb 4;61(3):474-85

Bartolomei G, Leutert M, Manzo M, Baubec T, Hottiger MO

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Poly(ADP-ribosyl)ation of Methyl CpG Binding Domain Protein 2 Regulates Chromatin Structure.

J Biol Chem 2016 Jan 15;

Becker A, Zhang P, Allmann L, Meilinger D, Bertulat B, Eck D, Hofstaetter M, Bartolomei G, Hottiger M, Schreiber V, Leonhardt H, Cardoso MC

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2015

ARTD1 Suppresses Interleukin 6 Expression by Repressing MLL1-Dependent Histone H3 Trimethylation.

Mol Cell Biol 2015 Sep 15;35(18):3189-99

Minotti R, Andersson A, Hottiger MO

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SnapShot: ADP-Ribosylation Signaling.

Mol Cell 2015 Jun 18;58(6):1134-1134.e1

Hottiger MO

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Latest publications

2017-06-27

The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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2017-05-26

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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2017-04-30

The impact of rare and low-frequency genetic variants in common disease.

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