Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications


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Group Leader:
Caroline Relton36 Publications.

2015

Aberrations in DNA methylation are detectable during remission of acute lymphoblastic leukemia and predict patient outcome.

Epigenomics 2015 Feb;7(1):35-45

van Otterdijk SD, Norden J, Dickinson AM, Pearce MS, Relton CL, Mathers JC, Strathdee G

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Biological embedding of early life exposures and disease risk in humans: a role for DNA methylation.

Eur J Clin Invest 2015 Jan 23;

Demetriou CA, van Veldhoven K, Relton C, Stringhini S, Kyriacou K, Vineis P

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Prenatal exposure to maternal smoking and offspring DNA methylation across the lifecourse: Findings from the Avon Longitudinal Study of Parents and Children (ALSPAC).

Hum Mol Genet 2014 Dec 30;

Richmond RC, Simpkin AJ, Woodward G, Gaunt TR, Lyttleton O, McArdle WL, Ring SM, Smith AD, Timpson NJ, Tilling K, Smith GD, Relton CL

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2014

Circulating biomarkers of one-carbon metabolism in relation to renal cell carcinoma incidence and survival.

J Natl Cancer Inst 2014 Dec;106(12)

Johansson M, Fanidi A, Muller DC, Bassett JK, Midttun O, Vollset SE, Travis RC, Palli D, Mattiello A, Sieri S, Trichopoulou A, Lagiou P, Trichopoulos D, Ljungberg B, Hallmans G, Weiderpass E, Skeie G, González CA, Dorronsoro M, Peeters PH, Bueno-de-Mesquita HB, Ros MM, Boutron Ruault MC, Fagherazzi G, Clavel F, Sánchez MJ, Gurrea AB, Navarro C, Quiros JR, Overvad K, Tjønneland A, Aleksandrova K, Vineis P, Gunter MJ, Kaaks R, Giles G, Relton C, Riboli E, Boeing H, Ueland PM, Severi G, Brennan P

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Prenatal Exposure to Maternal Cigarette Smoking and DNA Methylation: Epigenome-Wide Association in a Discovery Sample of Adolescents and Replication in an Independent Cohort at Birth through 17 Years of Age.

Environ Health Perspect 2014 Oct 17;

Lee KW, Richmond R, Hu P, French L, Shin J, Bourdon C, Reischl E, Waldenberger M, Zeilinger S, Gaunt T, McArdle W, Ring S, Woodward G, Bouchard L, Gaudet D, Davey-Smith G, Relton C, Paus T, Pausova Z

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A prospective study of one-carbon metabolism biomarkers and cancer of the head and neck and esophagus.

Int J Cancer 2014 Jun 28;

Fanidi A, Relton C, Ueland PM, Midttun O, Vollset SE, Travis RC, Trichopoulou A, Lagiou P, Trichopoulos D, Bueno-de-Mesquita HB, Ros M, Boeing H, Tumino R, Panico S, Palli D, Sieri S, Vineis P, Sánchez MJ, Huerta JM, Barricarte Gurrea A, Luján-Barroso L, Quirós JR, Tjønneland A, Halkjaer J, Boutron-Ruault MC, Clavel-Chapelon F, Cadeau C, Weiderpass E, Johansson M, Riboli E, Brennan P, Johansson M

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DNA methylation signatures in cord blood associated with maternal gestational weight gain: results from the ALSPAC cohort.

BMC Res Notes 2014 May 2;7(1):278

Morales E, Groom A, Lawlor DA, Relton CL

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Valproic acid triggers increased mitochondrial biogenesis in POLG-deficient fibroblasts.

Mol Genet Metab 2014 Mar 28;

Sitarz KS, Elliott HR, Karaman BS, Relton C, Chinnery PF, Horvath R

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What is it about boys?

Int J Epidemiol 2014 Feb;43(1):5-7

Relton CL

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Differences in smoking associated DNA methylation patterns in South Asians and Europeans.

Clin Epigenetics 2014 Feb 3;6(1):4

Elliott HR, Tillin T, McArdle WL, Ho K, Duggirala A, Frayling TM, Davey Smith G, Hughes AD, Chaturvedi N, Relton CL

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Latest publications

2017-06-27

The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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2017-05-26

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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2017-04-30

The impact of rare and low-frequency genetic variants in common disease.

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