Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications


Information is retrieved from

pubmed

Back to the index page

Group Leader:
Alfonso Valencia58 Publications.

2017

Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types.

Genome Biol 2017 Jan 26;18(1):18

Ecker S, Chen L, Pancaldi V, Bagger FO, Fernández JM, Carrillo de Santa Pau E, Juan D, Mann AL, Watt S, Casale FP, Sidiropoulos N, Rapin N, Merkel A, BLUEPRINT Consortium., Stunnenberg HG, Stegle O, Frontini M, Downes K, Pastinen T, Kuijpers TW, Rico D, Valencia A, Beck S, Soranzo N, Paul DS

View on PubMed

2016

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

Cell 2016 Nov 17;167(5):1415-1429.e19

Astle WJ, Elding H, Jiang T, Allen D, Ruklisa D, Mann AL, Mead D, Bouman H, Riveros-Mckay F, Kostadima MA, Lambourne JJ, Sivapalaratnam S, Downes K, Kundu K, Bomba L, Berentsen K, Bradley JR, Daugherty LC, Delaneau O, Freson K, Garner SF, Grassi L, Guerrero J, Haimel M, Janssen-Megens EM, Kaan A, Kamat M, Kim B, Mandoli A, Marchini J, Martens JH, Meacham S, Megy K, O'Connell J, Petersen R, Sharifi N, Sheard SM, Staley JR, Tuna S, van der Ent M, Walter K, Wang SY, Wheeler E, Wilder SP, Iotchkova V, Moore C, Sambrook J, Stunnenberg HG, Di Angelantonio E, Kaptoge S, Kuijpers TW, Carrillo-de-Santa-Pau E, Juan D, Rico D, Valencia A, Chen L, Ge B, Vasquez L, Kwan T, Garrido-Martín D, Watt S, Yang Y, Guigo R, Beck S, Paul DS, Pastinen T, Bujold D, Bourque G, Frontini M, Danesh J, Roberts DJ, Ouwehand WH, Butterworth AS, Soranzo N

View on PubMed

Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.

Cell 2016 Nov 17;167(5):1398-1414.e24

Chen L, Ge B, Casale FP, Vasquez L, Kwan T, Garrido-Martín D, Watt S, Yan Y, Kundu K, Ecker S, Datta A, Richardson D, Burden F, Mead D, Mann AL, Fernandez JM, Rowlston S, Wilder SP, Farrow S, Shao X, Lambourne JJ, Redensek A, Albers CA, Amstislavskiy V, Ashford S, Berentsen K, Bomba L, Bourque G, Bujold D, Busche S, Caron M, Chen SH, Cheung W, Delaneau O, Dermitzakis ET, Elding H, Colgiu I, Bagger FO, Flicek P, Habibi E, Iotchkova V, Janssen-Megens E, Kim B, Lehrach H, Lowy E, Mandoli A, Matarese F, Maurano MT, Morris JA, Pancaldi V, Pourfarzad F, Rehnstrom K, Rendon A, Risch T, Sharifi N, Simon MM, Sultan M, Valencia A, Walter K, Wang SY, Frontini M, Antonarakis SE, Clarke L, Yaspo ML, Beck S, Guigo R, Rico D, Martens JH, Ouwehand WH, Kuijpers TW, Paul DS, Stunnenberg HG, Stegle O, Downes K, Pastinen T, Soranzo N

View on PubMed

Somatic embryonic FGFR2 mutations in keratinocytic epidermal nevi.

J Invest Dermatol 2016 Apr 18;

Toll A, Fernández LC, Pons T, Groesser L, Sagrera A, Carrillo-de Santa Pau E, Vicente A, Baselga E, Vázquez M, Beltrán S, Pisano DG, Rueda D, Gut M, Pujol RM, Hafner C, Gut I, Valencia A, Real FX

View on PubMed

ISCB's Initial Reaction to The New England Journal of Medicine Editorial on Data Sharing.

PLoS Comput Biol 2016 Mar;12(3):e1004816

Berger B, Gaasterland T, Lengauer T, Orengo C, Gaeta B, Markel S, Valencia A

View on PubMed

Epigenomic Co-localization and Co-evolution Reveal a Key Role for 5hmC as a Communication Hub in the Chromatin Network of ESCs.

Cell Rep 2016 Feb 9;14(5):1246-57

Juan D, Perner J, Carrillo de Santa Pau E, Marsili S, Ochoa D, Chung HR, Vingron M, Rico D, Valencia A

View on PubMed

2015

Erratum to: The UBC-40 Urothelial Bladder Cancer Cell Line Index: a genomic resource for functional studies.

BMC Genomics 2015 Nov 30;16(1):1019

Earl J, Rico D, Carrillo-de-Santa-Pau E, Rodríguez-Santiago B, Méndez-Pertuz M, Auer H, Gómez G, Grossman HB, Pisano DG, Schulz WA, Pérez-Jurado LA, Carrato A, Theodorescu D, Chanock S, Valencia A, Real FX

View on PubMed

The potential clinical impact of the release of two drafts of the human proteome.

Expert Rev Proteomics 2015 Dec;12(6):579-93

Ezkurdia I, Calvo E, Del Pozo A, Vázquez J, Valencia A, Tress ML

View on PubMed

From residue coevolution to protein conformational ensembles and functional dynamics.

Proc Natl Acad Sci U S A 2015 Nov 3;112(44):13567-72

Sutto L, Marsili S, Valencia A, Gervasio FL

View on PubMed

wKinMut-2: Identification and Interpretation of Pathogenic Variants in Human Protein Kinases.

Hum Mutat 2015 Oct 7;

Vazquez M, Pons T, Brunak S, Valencia A, Izarzugaza JM

View on PubMed

Latest publications

2017-06-27

The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

Read more
2017-05-26

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

Read more
2017-04-30

The impact of rare and low-frequency genetic variants in common disease.

Read more