Colin Semple10 Publications.
Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation.
Mol Syst Biol 2015 Dec 23;11(12):852
Homozygous loss-of-function variants in European cosmopolitan and isolate populations.
Hum Mol Genet 2015 Jul 14;
Transcriptional dynamics reveal critical roles for non-coding RNAs in the immediate-early response.
PLoS Comput Biol 2015 Apr;11(4):e1004217
Sequence level mechanisms of human epigenome evolution.
Genome Biol Evol 2014 Jun 24;
Abundant local interactions in the 4p16.1 region suggest functional mechanisms underlying SLC2A9 associations with human serum uric acid.
Hum Mol Genet 2014 May 12;
An atlas of active enhancers across human cell types and tissues.
Nature 2014 Mar 27;507(7493):455-61
Corrigendum of 'High throughput analysis of epistasis in genome-wide association studies with BiForce'
Bioinformatics 2013 Oct 15;29(20):2667-2668
Properties of local interactions and their potential value in complementing genome-wide association studies.
PLoS One 2013;8(8):e71203
Side effects: substantial non-neutral evolution flanking regulatory sites.
PLoS Genet 2013 May;9(5):e1003528
Divergence of Mammalian higher order chromatin structure is associated with developmental Loci.
PLoS Comput Biol 2013 Apr;9(4):e1003017