Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

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Group Leader:
Richard Meehan33 Publications.


Lsh Is Essential for Maintaining Global DNA Methylation Levels in Amphibia and Fish and Interacts Directly with Dnmt1.

Biomed Res Int 2015;2015:740637

Dunican DS, Pennings S, Meehan RR

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Importance of investigating epigenetic alterations for industry and regulators: An appraisal of current efforts by the Health and Environmental Sciences Institute.

Toxicology 2015 Sep 1;335:11-9

Miousse IR, Currie R, Datta K, Ellinger-Ziegelbauer H, French JE, Harrill AH, Koturbash I, Lawton M, Mann D, Meehan RR, Moggs JG, O'Lone R, Rasoulpour RJ, Pera RA, Thompson K

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5-Hydroxymethylcytosine Profiling in Human DNA.

Methods Mol Biol 2015 Jul 1;

Thomson JP, Nestor CE, Meehan RR

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DNA immunoprecipitation semiconductor sequencing (DIP-SC-seq) as a rapid method to generate genome wide epigenetic signatures.

Sci Rep 2015 May 14;5:9778

Thomson JP, Fawkes A, Ottaviano R, Hunter JM, Shukla R, Mjoseng HK, Clark R, Coutts A, Murphy L, Meehan RR

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Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems.

Genome Biol 2015 Feb 4;16(1):11

Nestor CE, Ottaviano R, Reinhardt D, Cruickshanks HA, Mjoseng HK, McPherson RC, Lentini A, Thomson JP, Dunican DS, Pennings S, Anderton SM, Benson M, Meehan RR

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Emerging spectrum of deployment-related respiratory diseases.

Curr Opin Pulm Med 2015 Jan 8;

Krefft SD, Meehan R, Rose CS

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Epigenetic modification of the PD-1 (Pdcd1) promoter in effector CD4+ T cells tolerized by peptide immunotherapy.

Elife 2014 Dec 29;3

McPherson RC, Konkel JE, Prendergast CT, Thomson JP, Ottaviano R, Leech MD, Kay O, Zandee SE, Sweenie CH, Wraith DC, Meehan RR, Drake AJ, Anderton SM

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Modules, networks and systems medicine for understanding disease and aiding diagnosis.

Genome Med 2014;6(10):82

Gustafsson M, Nestor CE, Zhang H, Barabási AL, Baranzini S, Brunak S, Chung KF, Federoff HJ, Gavin AC, Meehan RR, Picotti P, Pujana MA, Rajewsky N, Smith KG, Sterk PJ, Villoslada P, Benson M

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MBD4 Interacts with and Recruits USP7 to heterochromatic foci.

J Cell Biochem 2014 Oct 30;

Meng H, Harrison DJ, Meehan RR

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Dynamic changes in DNA modification states during late gestation male germ line development in the rat.

Epigenetics Chromatin 2014;7:19

Rose CM, van den Driesche S, Sharpe RM, Meehan RR, Drake AJ

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Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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The impact of rare and low-frequency genetic variants in common disease.

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