Advancing Epigenetics Towards Systems Biology

List of EpiGeneSys publications

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Group Leader:
Ho-Ryun Chung8 Publications.


High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila.

Mol Cell 2015 Oct 1;60(1):146-62

Ramírez F, Lingg T, Toscano S, Lam KC, Georgiev P, Chung HR, Lajoie BR, de Wit E, Zhan Y, de Laat W, Dekker J, Manke T, Akhtar A

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A link between Sas2-mediated H4 K16 acetylation, chromatin assembly in S-phase by CAF-I and Asf1, and nucleosome assembly by Spt6 during transcription.

FEMS Yeast Res 2015 Nov;15(7)

Reiter C, Heise F, Chung HR, Ehrenhofer-Murray AE

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Chromatin segmentation based on a probabilistic model for read counts explains a large portion of the epigenome.

Genome Biol 2015 Jul 24;16:151

Mammana A, Chung HR

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ChIP-exo signal associated with DNA-binding motifs provide insights into the genomic binding of the glucocorticoid receptor and cooperating transcription factors.

Genome Res 2015 Feb 26;

Starick SR, Ibn-Salem J, Jurk M, Hernandez C, Love MI, Chung HR, Vingron M, Thomas-Chollier M, Meijsing SH

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Inference of interactions between chromatin modifiers and histone modifications: from ChIP-Seq data to chromatin-signaling.

Nucleic Acids Res 2014 Nov 20;

Perner J, Lasserre J, Kinkley S, Vingron M, Chung HR

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Deletions of chromosomal regulatory boundaries are associated with congenital disease.

Genome Biol 2014 Sep 4;15(9):423

Ibn-Salem J, Köhler S, Love MI, Chung HR, Huang N, Hurles ME, Haendel M, Washington NL, Smedley D, Mungall CJ, Lewis SE, Ott CE, Bauer S, Schofield PN, Mundlos S, Spielmann M, Robinson PN

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Finding Associations among Histone Modifications Using Sparse Partial Correlation Networks.

PLoS Comput Biol 2013 Sep;9(9):e1003168

Lasserre J, Chung HR, Vingron M

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Inferring nucleosome positions with their histone mark annotation from ChIP data.

Bioinformatics 2013 Aug 28;

Mammana A, Vingron M, Chung HR

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Latest publications


The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

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The impact of rare and low-frequency genetic variants in common disease.

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