Advancing Epigenetics Towards Systems Biology


Coordinating Team

Scientific Coordinator:

Geneviève Almouzni

Deputy Coordinators:

Asifa Akhtar,
Wolf Reik,
Eran Segal

Bill Lyons Informatics Centre at the UCL Cancer Institute

Computational Cancer Genomic

Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, UK

Centromere identity

MRC Molecular Haematology Unit, University of Oxford, United Kingdom

Switching genes on and off during haematopoiesis

Cancer Research UK London Research Institute

Developmental Signalling

Institute of Veterinary Biochemistry and Molecular Biology, University of Zurich, CH-8057 Zurich, Switzerland

Chromatin-wide analysis of dynamic histone ADP-ribosylation

The Babraham Institute, Cambridge, United Kingdom

Modelling the influence of current epigenetic information on future actions

Department of Computational & Systems Biology, John Innes Centre, Norwich, United Kingdom

Epigenetic Dynamics

Adolf Butenandt Institute, Ludwig-Maximilians-University, Munich, Germany


Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany

Epigenetic Control by Histone Methylation

Hospital Sant Joan de Déu, Fundació Sant Joan de Déu, Barcelona

Epigenetics and disease risk

University Medical Center Göttingen, Clinic for General, Visceral and Pediatric Surgery, Göttingen, Germany

Epigenomic regulation of tumor and stem cell properties

Molecular Biology Institute of Barcelona-CSIC, Spain

Chromatin regulation of human and viral gene expression

Molecular Biology Department, Wageningen University, Wageningen, The Netherlands

Analysis of transcription factor DNA binding sites in plants

The Babraham Institute, Cambridge, United Kingdom

A systems approach to understanding DNA methylation in germ cells and its consequences in development

Department of Biological Sciences - University of Cyprus

Epigenetic regulation of gene expression

Department of Molecular Biology, Adolf Butenandt Institut, Ludwig-Maximilians-Universität Munich, Germany

Nucleosome positioning and remodelling in yeast

Department of Physiological Chemistry, Adolf Butenandt Institut, Ludwig-Maximilians-Universität Munich, Germany

Molecular mechanisms of chromatin plasticity

Wellcome Trust Centre for Gene Regulation and Expression, The College of Life Sciences at the University of Dundee, UK

Nuclear structure and gene expression

Université Paul Sabatier, Toulouse III, Toulouse, France

Chromatin and DNA repair

Genetic Systems, EMBL-CRG Systems Biology and ICREA, Centre for Genomic Regulation (CRG), Barcelona, Spain

Inter-individual variation

Signalling ISP, Babraham Institute, CB22 3AT, Cambridge, UK

Mathematical modelling of signalling, gene transcription, epigenetics and metabolism

Computer Laboratory, University of Cambridge, Cambridge, United Kingdom

Statistical Bioinformatics, Systems Biology, Mathematical modeling

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

Chromosome Dynamics

Cancer Research UK, London Research Institute


Veterinary faculty, University of Ljubljana and Medical faculty, University of Maribor

Behavioral neuroendocrinology

European Bioinformatics Institute, European Molecular Biology Laboratory, Cambridge, United Kingdom

Computational and Evolutionary genomics, with a particular focus on single-cell biology