Advancing Epigenetics Towards Systems Biology

Stephan Beck

Department of Cancer Biology at the at UCL Cancer Institute, University College London, UK

Epigenomics in Health & Disease

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stephan beck

The Beck lab has broad interests in the genomics and epigenomics of phenotypic plasticity in health and disease. In addition to genetic variations, we study epigenetic variations such as DNA methylation, histone modifications and microRNAs and how they modulate genome function. Central to our research is the development of systems approaches for integration of multi-dimensional data and their application to epigenome-wide association studies (EWAS) in cancer and other common diseases to advance translational, regenerative and personalized medicine. Our contribution to EpiGeneSys is to explore and quantify the link between genotype and epigenotype in the context of common disease.

Latest publications

Validation of the MethylationEPIC BeadChip for fresh-frozen and formalin-fixed paraffin-embedded tumours.

28392843 - 2017-04-11
Clin Epigenetics 2017;9:33

Kling T, Wenger A, Beck S, Carén H

Epigenome-wide association studies for cancer biomarker discovery in circulating cell-free DNA: technical advances and challenges.

28391083 - 2017-04-10
Curr Opin Genet Dev 2017 Feb 16;42:48-55

Tanić M, Beck S

Epigenetic variation taking center stage in immunological research.

28322579 - 2017-03-23
Epigenomics 2017 Apr;9(4):375-378

Ecker S, Beck S

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