An ambitious EC-funded research initiative on epigenetics advancing towards systems biology

Institute of Molecular Biology (IMB), Mainz, Germany

Description

The newly founded Institute of Molecular Biology gGmbH (IMB) is a Centre of Excellence for Life Sciences, funded by the Boehringer Ingelheim Foundation, and located in Mainz, Germany. Applications are invited for a postdoctoral researcher position in the laboratory of Dr. Vijay Tiwari (www.imb-mainz.de/research-at-imb/tiwari).The successful applicant will contribute to internationally competitive research on Epigenetic Regulation of Cellular Differentiation.
The group employs high-throughput epigenomics assays such as ChIP-seq and RNA-seq in combination with stem cell biology and cutting-edge epigenetics and molecular biology tools and further aims to complement this outstanding research with novel assays in proteomics. The resulting datasets are analysed using computational biology approaches to generate a comprehensive model of chromatin-mediated transcriptional control during cellular differentiation.

You will

• Study epigenetic regulatory mechanisms that contribute to cellular differentiation
• Design and establish novel assays to unravel protein-protein interaction networks involved in epigenetic regulation during stem cell differentiation
• Uncover gene regulatory protein interaction networks at systems biology level in partnership with other experimental researchers and computational biologists in the lab\
• Utilize mouse embryonic stem cell differentiation and mouse as a model system 
• Obtain training in epigenomics, computational biology, stem cell biology, developmental biology, cell signalling and proteomics 
• Have access to all IMB Core Facilities
• Work in close collaboration with the group leader and other group members
• Collaborate with internal and external partners

Qualifications

Required Qualifications

• PhD and experience in some of the following areas: Biochemistry, Proteomics, Molecular Biology, Epigenetics or Epigenomics
• At least one first author paper in an international peer reviewed journal 
• Excellent written and spoken English
• Extensive expertise in various cloning methodologies as well as state of the art methods to identify protein-protein interactions. Experience in mass-spectrometry based methods would be a plus. 
• Competitiveness at the international level and willing to collaborate with internal and external collaborators as well as support other group members

Salary

We offer

• The possibility to work on cutting-edge projects using state-of-the-art technology
• A stimulating, diverse and international research environment 
• Advanced training opportunities 
• Career development 
• Competitive salary 
• Favourable pension scheme

Application details

To apply, please email a cover letter, your CV (in English), contact address of at least two professional referees and certificates of your degrees quoting Ref. No. #VTPD01 to This e-mail address is being protected from spambots. You need JavaScript enabled to view it . Informal enquires should be addressed to Dr. Vijay Tiwari ( This e-mail address is being protected from spambots. You need JavaScript enabled to view it ). IMB is an equal opportunity employer.

Relavant web link: http://www.imb-mainz.de

Starting date: 2012-10-01 or later Duration: Initially 2 years; option of further extension.
Closing date: 2012-09-30