An ambitious EC-funded research initiative on epigenetics advancing towards systems biology

Institut de Genetique Humaine

Description

Alternative splicing is an important process to generate protein diversity that affects the vast majority of human genes. Misregulation of cell-specific splicing programs can lead to disease, such as cancer. In the past few years, transcriptional regulators, chromatin conformation, histone modifications and non-coding RNAs have been shown to play a role in the regulation of alternative splicing (Luco et al, 2011 Cell). We recently found that histone marks directly regulate alternative splicing via recruitment of splicing factors by chromatin-adaptor complexes (Luco et al, 2010 Science). To continue these studies in my laboratory at the Institute of Human Genetics (IGH-CNRS), I am looking for a highly motivated, independent and creative post-doctoral fellow with strong background in molecular and cell biology. IGH is a very stimulating international institute in an extremely charming and sunny city, Montpellier (South of France).

Qualifications

PhD degree, good English, collaborative and motivated personality

Application details

If interested, please send a CV, e-mail contact for three reference letters and a brief cover letter stating research interests and career goals to :
Reini F. Luco - This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Starting date: 2012-05-01
Closing date: 2013-01-01