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A dominant allele of a gene gives rise to the entire phenotype in a heterozygous lineage/ organism; the other allele being repressed (recessive). Overdominance is a phenomenon where the heterozygous individual has an advantage over the homozygote, as the repressed allele gives rise to a partial phenotype with an advantage. For instance being heterozygous ...
Section: Content | Category: FAQ common | Date: Wednesday, 14 January 2015 | Hits: 717
We're all well aware that a difficult childhood can have a great impact on the course of someone's life. Childhood abuse can even drive individuals to commit suicide. A study published in Nature Neuroscience this month elucidates the molecular basis of how stress can shape the way genes work [...] We're all well aware that a difficult ...
Section: Content | Category: In brief | Date: Monday, 02 February 2009 | Hits: 13355
Two RISE 1 investigators have published a report mechanism that may lead to more efficient reprogramming of somatic cells The team of researchers around Maria-Elena Torres-Padilla (Institute of Genetics and Molecular and Cellular Biology, Strasbourg) and Juanma Vaquerizas (Max Planck Institute for Molecular Biomedicine, Münster) have managed to obtain ...
Section: Content | Category: News | Date: Wednesday, 19 August 2015 | Hits: 4462
Dr Lindsey Goff explores the effects of parenting on our molecular heritage. You could say that parenting begins at conception, when a unique mélange of DNA is born. This genetic mélange – your genome – is one of the few permanencies in life. It grows older with you and, except when mutated [...] June 2010 Dr Lindsey Goff explores the effects ...
Section: Content | Category: Features | Date: Tuesday, 01 June 2010 | Hits: 35828
... Grossniklaus, Selected aspects of transgenerational epigenetic inheritance and resetting in plants. Current opinion in plant biology14, 195 (Apr, 2011). 16. U. C. Lange, R. Schneider, What an epigenome remembers. BioEssays : news and reviews in molecular, cellular and developmental biology32, 659 (Aug, 2010). 17. T. Sexton et al., Three-dimensional ...
Section: Content | Category: Features | Date: Wednesday, 14 November 2012 | Hits: 34462
... can then be tested experimentally.Pictures adaped from:A. vandenBerg, L. Ringrose, First annual meeting of the EpiGeneSys Network of Excellence: moving epigenetics towards systems biology. BioEssays : news and reviews in molecular, cellular and developmental biology34, 620 (Jul, 2012). Systems Biology approaches are promising to help scientists advance ...
Section: Content | Category: In brief | Date: Friday, 16 November 2012 | Hits: 21069
Response written by: Elphège Nora, PhD - postdoctoral researcher in Edith Heard's laboratory, Institut Curie Strictly speaking, the word "epigenetic" characterizes the mode of inheritance of a given trait, irrespective of the molecular mechanism or process that underlies it. "Epigenetic process" and "epigenetic mechanisms" are synonymous expressions ...
Section: Content | Category: FAQ common | Date: Friday, 09 November 2012 | Hits: 4487
... on trying to understand what these nerves really modify in our neurons, down to the molecular level, depending on what sensation we feel and remember. This is surely a very exciting avenue of research! ...
Section: Content | Category: FAQ common | Date: Friday, 09 November 2012 | Hits: 2183
... Somervilles moved to Italy in 1838, where Mary would spend most of the rest of her life. Her most successful book, Physical geography, appeared in 1848. It was widely used by schools and universities for the following half a century. She went on to write two further books, Molecular and microscopic science and her autobiography, Personal Recollection ...
Section: Content | Category: Women in science | Date: Wednesday, 02 January 2013 | Hits: 10522
... the cellular state (blood, skin, etc...) is somehow instructed from the parental mother cell to the daughter cell. There are many molecular mechanisms that play a role in this process and researchers are actively trying to understand them. What John Gurdon and Shinya Yamanaka understood is how to actually interfere with this process, and force a cell ...
Section: Content | Category: FAQ common | Date: Friday, 09 November 2012 | Hits: 2454
... from eng) Nature structural & molecular biology 14(11):1025-1040 (in eng). 5. Michalak P (2006) RNA world - the dark matter of evolutionary genomics. J Evol Biol 19(6):1768-1774. Photo by:p_a_h http://www.flickr.com/photos/pahudson/ We know that in some cases, small RNAs (20-30n) can guide the modification of DNA or histones at specific ...
Section: Content | Category: Features | Date: Tuesday, 05 March 2013 | Hits: 15327
... Russia. When not busy with her PhD-research in molecular biology, Diana is engaged in photography and visual art, especially focusing on fluorescent art, which reflects her magic vision of the balance of life between stability and flexibility. Laurent DerobertDoctor of economic sciences and researcher, Laurent Derobert has been developing "existential ...
Section: Content | Category: News | Date: Thursday, 09 April 2015 | Hits: 7291
... the nucleus and its dynamic context has remained an elusive challenge until recently with the advent of new technologies. As many other emerging areas in science, ours is a technology driven field. The challenge in the 4DNucleome Initiative includes advanced technologies from four interdisciplinary fields at its core: cell biology, molecular genetics, ...
Section: Content | Category: News | Date: Tuesday, 03 May 2016 | Hits: 2338
... Deoxyribonucleic acid, or DNA as it is most commonly known, is often described as the blueprint or code of all living organisms.At the time, the genetic significance of DNA was widely recognised but no one knew what it looked like at the molecular level – and Franklin’s research was to lay the groundwork for identifying the distinct double-helix structure ...
Section: Content | Category: Women in science | Date: Monday, 06 May 2013 | Hits: 15229
... Bird, no one really understands why. "That's where there's a gap." New advances in molecular biology are allowing scientists to paint a much more detailed picture of the epigenetic changes that happen over time in the brain. For many years, scientists thought that DNA methylation was a very stable epigenetic change. But recent work has called this ...
Section: Content | Category: Features | Date: Thursday, 04 April 2013 | Hits: 22877