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... marks are more like the dynamic notations, such as piano (quiet) or fortissimo (very loud), written on a musical score to indicate how the music should be played. If the genome is a musical score, then proteins like MeCP2 are orchestral conductors, reading the dynamics and coordinating the behaviour of the players involved in gene activity, making ...
Section: Content | Category: Features | Date: Thursday, 04 April 2013 | Hits: 22883
As of September 1, Geneviève Almouzni, CNRS Research Director, director of the Nuclear Dynamics and Genome Plasticity unit, and assistant director of the training unit has taken over the management of the Research Centre. She was selected by the Institut Curie's international Scientific Advisory Board, to replace Professor Daniel Louvard, who has held ...
Section: Content | Category: News | Date: Thursday, 29 August 2013 | Hits: 4856
... these cells may need to be further confirmed using other cell lines closer to the somatic cells, such as primary lines, in order to better understand and fight diseases such as cancer. Answered by: David Sitbon, Ph.D. Student, Unit "Nuclear Dynamics" UMR3664 CNRS/Institut Curie ...
Section: Content | Category: FAQ common | Date: Monday, 23 March 2015 | Hits: 13301
The science of collaboration The science of collaboration Name: Tatyana Ehrenfest-AfanasyevaNationality: Russian/DutchLived: 1876-1964Fields: Mathematics, physics and educationClaim to fame: Made major contributions to the foundations of statistical mechanics and statistical thermodynamics Close ...
Section: Content | Category: Women in science | Date: Friday, 29 March 2013 | Hits: 8065
... on hydrodynamics and, based on her knowledge of air vortices, invented the Ayrton fan, a cheap and simple device that could be used to clear poisonous gas from trenches. ...
Section: Content | Category: Women in science | Date: Monday, 18 March 2013 | Hits: 13526
... fur. Just as the conductor of an orchestra controls the dynamics of a symphonic performance, epigenetic factors govern the interpretation of DNA within each living cell. Understanding these factors could revolutionize evolutionary and developmental biology, and thus affect practices from medicine to agriculture. To answer Watson, "The genetic alphabet ...
Section: Content | Category: In brief | Date: Thursday, 01 June 2006 | Hits: 18650
... for this. Systems Biology approaches are therefore very promising to help us advance the field of Epigenetics via gaining a better understanding of the dynamics of epigenetic regulators, the nature of signaling affecting the epigenome and the link between genotype and epigenotype. References: 1. F. Marcus, Bioinformatics and Systems Biology: Collaborative ...
Section: Content | Category: In brief | Date: Friday, 16 November 2012 | Hits: 21069
... transcription factors that determine cell fate. References: 6. Mellor J (2005) The dynamics of chromatin remodeling at promoters. (Translated from eng) Molecular cell 19(2):147-157 (in eng). 7. Vermeulen M, et al. (2007) Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4. Cell 131(1):58-69. Photo by:TheJCBhttp://www.flickr.com/photos/thejcb/ A ...
Section: Content | Category: Features | Date: Tuesday, 05 March 2013 | Hits: 15327
... differentiation. Genome is to a musical score as the epigenome to dynamics and phrasing Scientists know that different types of cell switch on different collections of genes. How they get to this point, however, is still an area of intense research. The behaviour of each gene is governed by associated regions of DNA. This influences the ...
Section: Content | Category: Features | Date: Monday, 03 September 2007 | Hits: 22354