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... to be addressed with newly funded FET FLAGSHIPS by 2018. The supporters of this initiative propose to the European Commission to launch a large-scale initiative aiming to decipher the structure-function relationships of the cell nucleus as a complex biological system at all levels, from molecules to entire genomic and epigenomic landscapes, as they ...
Section: Content | Category: News | Date: Tuesday, 03 May 2016 | Hits: 2338
Systems Biology approaches are promising to help scientists advance the field of Epigenetics.Systems biology is the study of systems of biological components. Since living systems are dynamic and complex, their behavior can be hard to predict [...] Systems biology uses information about the parts of the system (shown on the left) in order to ...
Section: Content | Category: In brief | Date: Friday, 16 November 2012 | Hits: 21070
... eng) Cell 128(4):635-638 (in eng). 3. Berger SL (2007) The complex language of chromatin regulation during transcription. (Translated from eng) Nature 447(7143):407-412 (in eng). 4. Taverna SD, Li H, Ruthenburg AJ, Allis CD, & Patel DJ (2007) How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers. (Translated ...
Section: Content | Category: Features | Date: Tuesday, 05 March 2013 | Hits: 15327
... statistical approach in mechanics, in 1911.The Ehrenfest-Afanasyeva review detailed the work of the Austrian physicist and his school, explaining statistical thermodynamics and irreversibility, and highlighting some fundamental contributions to statistical mechanics. This field of physics uses probability to predict the behaviour of a complex system. ...
Section: Content | Category: Women in science | Date: Friday, 29 March 2013 | Hits: 8065
... ill health and bursts of energy. This complex interplay manifested itself as early as 1828, when Ada mixed romanticism with science to produce a design for a flying machine. Numerical advantage Despite her passion for mathematics and obscure learning, Ada was a “dainty” socialite. At court, she danced often and was able to charm many people, including ...
Section: Content | Category: Women in science | Date: Friday, 04 January 2013 | Hits: 10278
... creation of complex organisms. The following year, she published another work in which she challenged the ideas expressed by contemporary natural philosophers. She had the two books dispatched by special messenger to the most celebrated scholars of the day.In 1666, Margaret published her Observations upon Natural Philosophy, which strongly criticised ...
Section: Content | Category: Women in science | Date: Wednesday, 28 November 2012 | Hits: 46706
Scientific American's Christine Gorman explains why the answer to this question is more complex than it first appears. Video from Scientific American, 10 August 2012 [online] ...
Section: Content | Category: Epigenetics & behavior | Date: Thursday, 23 August 2012 | Hits: 4466
... the desk of US President Woodrow Wilson, who later used them as inspiration for some of his own peace proposals (the ‘14 points‘).In the aftermath of the war, the WILPF continued to campaign vigorously against the use of poison gas in warfare and Gertrud, with her expertise in toxicology, coupled with her ability to explain complex subjects to the public, ...
Section: Content | Category: Women in science | Date: Tuesday, 02 April 2013 | Hits: 5801
... de physique (Lessons in physics). The book sought to reconcile complex ideas from the leading thinkers of the time, including the German, Dutch and English philosophers and mathematicians Gottfried Leibniz, Willem ‘s Gravesande and Isaac Newton. She showed that the energy of a moving object is proportional not to its velocity, as had previously been ...
Section: Content | Category: Women in science | Date: Friday, 14 December 2012 | Hits: 17458
... FlickrCC licenced by Researchers once thought the proteins that stick to epigenetic marks fell into two camps: "repressors", which turn gene activity off, and "activators", which turn gene activity on. But a flurry of findings over the past 5 years has pointed to a far more complex picture. Rather than being simple "on" or "off" switches, epigenetic ...
Section: Content | Category: Features | Date: Thursday, 04 April 2013 | Hits: 22884
... this motif is methylated. ZFP57 itself is part of a protein complex, which somehow keeps the DNA methyltransferases around these motifs. So while the imprinted genes keep on being continuously methylated in the embryo because the DNA methyltransferase enzymes are attached to them, the other sequences of the genome will lose their methylation.However, ...
Section: Content | Category: FAQ common | Date: Wednesday, 02 April 2014 | Hits: 5037
... including humans, scientists realised that they do not hold the key to fully explaining the mysteries of life and our evolution. Despite this considerable step forward we are still far away from being able to understand many diseases and identify promising cures. In fact, there is yet another level of complexity, which adds to fine tuning our genes: ...
Section: Content | Category: News | Date: Thursday, 09 April 2015 | Hits: 7291
Yes they do! And this ability of methyl groups to be copied at each round of DNA replication is what makes DNA methylation "epigenetics": the information carried by these methyl groups is faithfully and autonomously transmitted from the mother cell to its daughter cells. There is a specialized enzymatic complex, the DNA methylltransferase 1 (DNMT1), ...
Section: Content | Category: FAQ common | Date: Wednesday, 02 April 2014 | Hits: 8045
... flies (5) —but, we don't yet know if traits in humans can be transmitted across generations. Eric's result stands as one of the first examples of passing on a complex trait like longevity through several generations. As Jana Lim, currently a PhD student in Anne Brunet's lab at Stanford University in California, USA, explains, "It has been long thought ...
Section: Content | Category: Features | Date: Thursday, 18 July 2013 | Hits: 23192
... the Agricultural College and was given the title of assistant. She also lectured at FWU teaching heredity as part of the medical faculty between 1927 and 1945, having been granted the unpensioned position of ‘unofficial, extraordinary professor‘. Her strong teaching skills and ability to explain complex issues in a simple way soon won her the admiration ...
Section: Content | Category: Women in science | Date: Thursday, 18 April 2013 | Hits: 5037